Evidence map›Paper›PMID 40937559›Full record

ReviewInternational journal of molecular medicine2025

Exercise training for myocardial ischemia reperfusion injury: Mechanism and clinical practice (Review).

Junwei Gao, Lingyao Li, Siqi Zhai, Yan Dong, Zhiyi Zhang, Duomao Lin, Jun Ma

Abstract readReview
In one paragraph

Review in International journal of molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junwei GaoDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China.
Lingyao LiDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China.
Siqi ZhaiDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China.
Yan DongDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China.
Zhiyi ZhangDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China.
Duomao LinDepartment of Anesthesiology, The First Hospital of Tsinghua University, Beijing 100016, P.R. China.
Jun MaDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial ischemia reperfusion injury (MIRI) remains a key and difficult issue in the field of cardiovascular diseases, and its pathogenesis involves multiple aspects. Exercise can effectively improve MIRI, and the mechanisms include reducing oxidative stress and inflammatory responses, regulating mitochondrial function and metabolic abnormalities, and so on. For patients undergoing reperfusion, rehabilitation therapy mainly based on exercise has important clinical significance. The present study expounded on the occurrence of MIRI from the perspective of mechanisms and the improvement effect of exercise on MIRI, elaborates on the main current exercise strategies and existing problems from the aspect of clinical practice, and discusses the possible future development directions.

Indexed as

ExerciseExercise TherapyMyocardial Reperfusion InjuryAnimalsHumansOxidative Stresscardiac rehabilitationexercisemolecular mechanismmyocardial ischemia reperfusion injury

Identifiers

PMID40937559
PMCPMC12440276

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.