Evidence map›Paper›PMID 40937553›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

Progress towards HIV transmission elimination targets: model-based estimation of incidence and the extent of undiagnosed infection, Scotland, 1981 to 2022.

Scott A McDonald, Beth L Cullen, Lesley A Wallace, Alan Yeung, Rak Nandwani, Claudia Estcourt, Daniel Clutterbuck, Nicola Steedman, David Henderson, Kirsty Roy and 1 more

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Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Scott A McDonaldGlasgow Caledonian University, Glasgow, United Kingdom.
Beth L CullenPublic Health Scotland, Gyle Square, Edinburgh, United Kingdom.
Lesley A WallacePublic Health Scotland, Gyle Square, Edinburgh, United Kingdom.
Alan YeungGlasgow Caledonian University, Glasgow, United Kingdom.
Rak NandwaniGlasgow Caledonian University, Glasgow, United Kingdom.
Claudia EstcourtGlasgow Caledonian University, Glasgow, United Kingdom.
Daniel ClutterbuckChalmers Centre, NHS Lothian, Edinburgh, United Kingdom.
Nicola SteedmanGlasgow Caledonian University, Glasgow, United Kingdom.
David HendersonPublic Health Scotland, Gyle Square, Edinburgh, United Kingdom.
Kirsty RoyPublic Health Scotland, Gyle Square, Edinburgh, United Kingdom.
Sharon J HutchinsonGlasgow Caledonian University, Glasgow, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDThe global goal to end the AIDS epidemic cannot be achieved without estimates of incidence and undiagnosed infection.AIMWe aimed to estimate the timing of HIV transmission events and the number of people unaware of their diagnosis in Scotland, by mode of acquisition and migrant status.METHODSSurveillance data from Scotland's national HIV diagnosis database (1981-2022) linked to death and migration data was entered into the HIV Platform tool of the European Centre for Disease Prevention and Control, to back-calculate HIV incidence while imputing missing data and adjusting for reporting delay.RESULTSWe estimated 8,235 HIV transmission events between 1980 and 2022 among people living in Scotland, with an 80% reduction from 2010 to 2021 (258 to 52 events). Excluding people diagnosed outside Scotland, we estimated 4,854 (95% confidence interval (CI): 4,637-5,080) people living with HIV at the end of 2021, of whom 8.2% (396/4,854) were undiagnosed. Stratified estimates of this proportion were 6.9% for gay, bisexual and other men who have sex with men, 7.0% for people who inject drugs, 12.6% and 12.4% for heterosexuals born and not-born in the United Kingdom (UK), respectively. Including people first diagnosed with HIV outside Scotland, the overall proportion undiagnosed was 6.1% (396/6,444).CONCLUSIONScotland is on track to meet the United Nations' diagnosis target of 95% by 2025, with the World Health Organization target of a 75% incidence reduction met since 2010. To reduce further transmission, expanded HIV testing and prevention services are necessary to better reach at-risk heterosexual individuals.

Indexed as

Disease EradicationHIV InfectionsUndiagnosed DiseasesAdolescentAdultFemaleHomosexuality, MaleHumansIncidenceMaleMiddle AgedPopulation SurveillanceScotlandYoung AdultDiagnosisHIVModes of acquisitionScotlandTransmission

Identifiers

PMID40937553
PMCPMC12432492

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