ReviewFrontiers in cellular and infection microbiology2025
Emerging interplays between poxviruses and autophagy.
Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Exploration of the protein and pharmacological landscape of monkeypox virus treatment: from entry point to end point.Molecular diversity · 2026Review
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Authors and funding
4 authors.
Funding
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Abstract
Poxviruses are large double-stranded DNA viruses that replicate exclusively in the cytoplasm. Their life cycle is closely associated with various membrane-related cellular processes. This review summarizes current findings on the complex interplay between poxviruses and autophagy, as well as the endo-lysosomal network. However, due to the large diversity of poxvirus species and the limited number of relevant studies, it remains challenging to draw definitive conclusions regarding the bidirectional regulatory relationship between poxviruses and the autophagy-lysosome system. In addition, poxviruses can serve as a promising platform for oncolytic virus development. Furthermore, we also highlight recent studies leveraging autophagy modulation to enhance the therapeutic efficacy of oncolytic poxviruses. Thus, elucidation of the interplay between poxviruses and autophagy-lysosome pathway will not only advance the understanding of virology and cell biology, but also facilitate the engineering of oncolytic poxviruses as innovative tools for cancer therapy.
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