Evidence map›Paper›PMID 40937392›Full record

ReviewIndian journal of clinical biochemistry : IJCB2025

Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review.

Yasser Fakri Mustafa

Abstract readReview
In one paragraph

Review in Indian journal of clinical biochemistry : IJCB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yasser Fakri MustafaDepartment of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul, Iraq.ORCID 0000-0002-0926-7428

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains one of the most pressing global health concerns, ranking as the second leading cause of death worldwide. Oxidative stress plays a pivotal role in the initiation and progression of cancer, making antioxidants a critical area of research in cancer prevention and treatment. This review aims to provide a comprehensive analysis of fruit-derived antioxidants and their potential therapeutic applications in combating cancer. In particular, it looks at how bioactive compounds like flavonoids, polyphenols, and essential vitamins found in fruits help to neutralize reactive oxygen species, control gene activity, and stop tumors from spreading and growing. The review brings together new studies from the lab, on animals, and with people that show how fruit-derived antioxidants can help fight cancer, how they change important cellular pathways, and how they might work better when combined with other treatments. Furthermore, it discusses challenges related to bioavailability, standardization, and clinical translation, underscoring the need for more robust clinical trials. This review shows how important it is to include antioxidants from fruits in dietary guidelines and move forward with targeted research into their therapeutic use in cancer management. It does this by looking at the current evidence and pointing out research gaps. Graphical Abstract:

Indexed as

Bioactive compoundsCancer preventionCancer therapyFruit-derived antioxidantsOxidative stress

Identifiers

PMID40937392
PMCPMC12420558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.