Evidence map›Paper›PMID 40937391›Full record

ArticleIndian journal of clinical biochemistry : IJCB2025

The Effects of Alpha Linolenic Acid (Omega-3 Fatty Acid) on Tobacco Craving Intensity, Withdrawal Symptoms and Biochemical Markers in Tobacco Users.

Anjali Singh, Narsingh Verma, Surya Kant, Ajay Kumar Verma, Adarsh Tripathi, Kshitij Bhardwaj

Abstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synergistic Beneficial Effects of Flaxseed (Food science & nutrition · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anjali SinghDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.
Narsingh VermaDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.ORCID 0000-0003-0348-7419
Surya KantDepartment of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.
Ajay Kumar VermaDepartment of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.
Adarsh TripathiDepartment of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.
Kshitij BhardwajDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tobacco use causes serious public health concerns and causes many health problems like (asthma, COPD, stroke, cancer, etc.). While a number of pharmacological treatments are used to reduce tobacco use, they often have adverse effects. Fewer studies have assessed non-pharmacological treatments {Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA) or fish oil} to reduce tobacco use. Omega-3 fatty acids, already known for their benefits in reducing bad cholesterol, managing diabetes, and helping with fatty liver, are now being studied for their potential impact on smoking habits. We aimed to evaluate the effect of omega-3 supplementation (flaxseed oil as a vegetarian source of alpha-linolenic acid, ALA) on tobacco craving intensity, withdrawal symptoms, and various biochemical markers in tobacco users. This single-blind, placebo-controlled study involved 104 tobacco users divided into two groups: omega-3 (n = 54) receiving 10 ml flaxseed oil daily for 6 months and placebo (n = 50). We measured tobacco craving intensity {Visual Analogue Scale (VAS)}, withdrawal symptoms {Minnesota Nicotine Withdrawal Scale (MNWS)}, demographic parameters (BMI, WHR, BP, HR), and biochemical parameters (LFT, KFT, Lipid Profile) at baseline and after 6 months. Six-month consumption of edible grade pure flaxseed oil resulted in significant lowering of BMI in omega-3 group when compared to placebo group (

Indexed as

Alpha-linolenic acidSmokingTobacco cessationTobacco cravingWithdrawal

Identifiers

PMID40937391
PMCPMC12420553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.