Evidence map›Paper›PMID 40937371›Full record

ReviewJournal of biological methods2025

Differential diagnosis of Hashimoto's thyroiditis: The importance of pathological anatomy.

Hernando Vargas-Uricoechea, Ivonne Meza-Cabrera, Alejandro Castellanos-Pinedo, Karen Urrego-Noguera, María V Pinzón-Fernández

Abstract readReview
In one paragraph

Review in Journal of biological methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hernando Vargas-UricoecheaDepartment of Internal Medicine, Faculty of Health Sciences, University of Cauca, Popayán, 190001 Cauca, Colombia.
Ivonne Meza-CabreraDepartment of Pathology, Faculty of Health Sciences, University of Cauca, Popayán, 190001 Cauca, Colombia.
Alejandro Castellanos-PinedoDepartment of Internal Medicine, Faculty of Medicine, University of Sinú, Hospital San Jerónimo, Montería, 230001 Córdoba, Colombia.
Karen Urrego-NogueraDepartment of Internal Medicine, Faculty of Health Sciences, University of Cauca, Popayán, 190001 Cauca, Colombia.
María V Pinzón-FernándezDepartment of Internal Medicine, University of Cauca, Popayán, 190001 Cauca, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hashimoto's thyroiditis (HT) represents a complex, multifactorial autoimmune disease characterized by a broad spectrum of clinical and imaging presentations. These manifestations tend to be clinically perplexing, necessitating additional tests. In cases where a malignancy is suspected or obstructive symptoms are present, surgical management may be required. Histopathologically, HT is hallmarked by significant lymphocytic infiltration of the thyroid gland, typically with prominent germinal centers, small lymphocytes, centrocytes, centroblasts, plasma cells, and occasionally immunoblasts. The degree of fibrosis varies, giving the gland a lobulated appearance and, in some cases, resulting in a fibrous variant, which, biochemically, is usually accompanied by hypothyroidism. Objective: This review provided a diagnostic and differential approach to HT, highlighting the utility of histopathological examination. Conclusion: Histopathological analysis helps broaden the diagnostic and therapeutic horizon in individuals with HT.

Indexed as

AutoimmunityHashimotoHistopathologyThyroiditis

Identifiers

PMID40937371
PMCPMC12422120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.