Evidence map›Paper›PMID 40937097›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Preliminary Short-Term Results of Supraciliary Ab-Interno MINIject

Jan Niklas Lüke, Vincent Lüke, Thomas Dietlein, Johanna Wiedemann, Alexandra Lappas

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jan Niklas LükeDepartment of Ophthalmology, Medical Faculty and University Hospital of Cologne, Cologne, 50937, Germany.
Vincent LükeDepartment of Ophthalmology, Medical Faculty and University Hospital of Cologne, Cologne, 50937, Germany.
Thomas DietleinDepartment of Ophthalmology, Medical Faculty and University Hospital of Cologne, Cologne, 50937, Germany.
Johanna WiedemannDepartment of Ophthalmology, Medical Faculty and University Hospital of Cologne, Cologne, 50937, Germany.
Alexandra LappasDepartment of Ophthalmology, Medical Faculty and University Hospital of Cologne, Cologne, 50937, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the efficacy of MINIject Methods: In this single-center retrospective study, 18 patients who had undergone suprachoroidal stent implantation after failed filtering surgery were analyzed. Follow-up was at least 12 months, and surgical success was measured by 12-month postoperative intraocular pressure (IOP), glaucoma medication, and revision surgery (criteria A: IOP < 21 mmHg, IOP reduction >20%, no revision surgery; criteria B: IOP < 18 mmHg, IOP reduction >20%, no revision surgery; criteria C: IOP ≤ 15 mmHg, IOP reduction ≥40%, no repeat surgery). Results: After a follow-up period of 12 months, the mean IOP decreased from 27.11±5.65 mmHg to 15.94±9.56 mmHg (p<0.01). The median 12-month postoperative IOP was 14.0 mmHg (IQR: 10.0-20.0 mmHg). The probability of surgical success was 66.66% for criteria A and B and 50% for criteria C. The identical success rates for criteria A and B were due to overlapping responder groups in this limited sample. Topical medication was significantly reduced from 4.06±1.08 to 2.13±1.36 (p<0.0001). Conclusion: Supraciliary stent implantation provided an effective and safe treatment option for advanced glaucoma following failed filtering surgery and demonstrated significant intraocular pressure reduction. However, the small sample size limits the generalizability of these findings.

Indexed as

CyPass Micro-Stentglaucoma drainage deviceintraocular pressureMIGSsupraciliarytrabeculectomy

Identifiers

PMID40937097
PMCPMC12420924

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