Evidence map›Paper›PMID 40937016›Full record

ArticleCureus2025

Clinical Course of Iris Retraction Syndrome Associated With Rhegmatogenous Retinal Detachment: A Report of Three Cases.

Keigo Takagi, Kazunobu Sugihara, Mizuki Iida, Kana Murakami, Chisako Ida, Hinako Ohtani, Masaki Tanito

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Keigo TakagiDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Kazunobu SugiharaDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Mizuki IidaDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Kana MurakamiDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Chisako IdaDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Hinako OhtaniDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes three cases of iris retraction syndrome (IRS) associated with long-standing rhegmatogenous retinal detachment (RRD), all presenting with hypotony, abnormally deep anterior chambers, and ciliary body detachment, often accompanied by dense cataracts and uveitis-like findings that initially obscured the underlying pathology. In each case, anti-inflammatory therapy led to partial resolution of anterior segment abnormalities, subsequently revealing RRD that required pars plana vitrectomy with or without combined cataract surgery. Postoperatively, most cases maintained stable IOP, although one developed secondary ocular hypertension necessitating glaucoma therapy. These cases highlight that IRS can mask its primary cause; careful evaluation for RRD or other causes is warranted when posterior iris bowing is observed in hypotonic eyes, and long-term IOP monitoring remains important even after successful treatment of the underlying pathology.

Indexed as

anterior segment optical coherence tomographyciliary body detachmenthypotonyintraocular pressureiris retraction syndromeproliferative vitreoretinopathyrhegmatogenous retinal detachmentuveitis-like presentation

Identifiers

PMID40937016
PMCPMC12422068

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.