Evidence map›Paper›PMID 40936969›Full record

ArticleACG case reports journal2025

Brucellosis. A Rare Cause of Biliary Dysplasia and Ampullary Adenocarcinoma?

Zachary Vinton, Kevin Wolfe, Sean MacBride, Thomas Heffron, Vimal Jhaveri, Andrea K Sotelo, Mark Rosenblatt, Clark Kulig, Matthew Stotts

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zachary VintonDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, NE.ORCID https://orcid.org/0009-0005-6254-4972
Kevin WolfeDepartment of Internal Medicine, Hennepin Health, Minneapolis, MN.
Sean MacBrideSchool of Medicine, University of Nebraska Medical Center, Omaha, NE.
Thomas HeffronDepartment of Transplant Hepatology, Porter Hospital, Denver, CO.
Vimal JhaveriWestern Infectious Disease Consultants, Denver, CO.
Andrea K SoteloHCA Pathology Services, Presbyterian St. Luke's, Denver, CO.
Mark RosenblattDepartment of Gastroenterology and Hepatology, UCHealth Longs Peak Hospital, Longmont, CO.
Clark KuligDepartment of Transplant Hepatology, Porter Hospital, Denver, CO.
Matthew StottsDepartment of Transplant Hepatology, Porter Hospital, Denver, CO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brucellosis, a zoonotic bacterial infection often characterized by nonspecific symptoms including fever, night sweats, and weight loss, has a prolonged and recurrent course, often leading to chronic symptoms if inadequately treated. Hepatic involvement is well-documented with manifestations ranging from mild hepatitis to hepatic abscesses and granulomas. However, the association of brucellosis with biliary dysplasia or ampullary adenocarcinoma has not been previously reported in medical literature. We present a 68-year-old man with hepatic granulomatosis due to chronic brucellosis complicated by numerous episodes of ascending cholangitis secondary to choledocholithiasis and common bile duct strictures, with high-grade dysplasia and development of ampullary adenocarcinoma.

Identifiers

PMID40936969
PMCPMC12422768

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.