A rare case of late chromophobe RCC metastasis with indolent course.

Periklis Anastasiou, Konstantinos Douroumis, Panagiotis Panagopoulos, Panagiotis Katsikatsos, Christos Kalfountzos, Spyridon Davakis, Ioannis Anastasiou

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Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Periklis AnastasiouFaculty of Medicine, School of Health Sciences, University of Ioannina, Bizani, Ioannina, 45500, Greece.

Konstantinos DouroumisFirst Department of Urology, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

Panagiotis PanagopoulosFirst Department of Urology, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

Panagiotis KatsikatsosFirst Department of Urology, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

Christos KalfountzosFirst Department of Urology, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

Spyridon DavakisFirst Department of Surgery, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

Ioannis AnastasiouFirst Department of Urology, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

Funding

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6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is the predominant solid lesion of the kidney. Among the various subtypes of RCC, chromophobe RCC (chRCC) is relatively rare, and it is characterized by an indolent clinical course and a favourable prognosis. We present a rare case of a 40-year-old patient who developed a retroperitoneal metastasis four years after undergoing radical nephrectomy for chRCC. The patient was under surveillance for another six years before surgical excision of the recurrence was performed. This case underscores the potential for late recurrence in chRCC and highlights the importance of long-term surveillance, even in patients with an initially favourable prognosis.

Indexed as

ChromophobeMetastasectomyRenal cell carcinomaRetroperitoneum

Identifiers

PMID40936937

DOI10.1016/j.eucr.2025.103180

PMCPMC12421628

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