Evidence map›Paper›PMID 40936874›Full record

ArticleJournal of orthopaedic case reports2025

Rare Case of Heterotopic Ossification Impinging on the Quadriceps Mechanism Following Total Knee Replacement: A Case Report.

M S Karthik, Abrar Mohammed, Avinash Parthasarathy

Abstract readCase Reports
In one paragraph

Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M S KarthikDepartment of Arthroplasty, Sanjay Gandhi Institute of Trauma and Orthopedics, Bengaluru, Karnataka, India.
Abrar MohammedDepartment of Arthroplasty, Sanjay Gandhi Institute of Trauma and Orthopedics, Bengaluru, Karnataka, India.
Avinash ParthasarathyDepartment of Arthroplasty, Sanjay Gandhi Institute of Trauma and Orthopedics, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Heterotopic ossification (HO) is a rare complication following total knee replacement (TKR), with an incidence ranging between 1% and 3%. This condition can lead to significant functional limitations, including immobility and pain, particularly when ossification impinges on adjacent structures. Case Report: We report the case of a 67-year-old female with grade 4 osteoarthritis of the left knee who underwent TKR following the failure of conservative management. Postoperatively, the patient developed stiffness and a reduced range of motion. Radiographic imaging at 5 weeks showed haziness in the anterior aspect of the femur at the upper border of the femoral implant, with gradual progression to distinct ossification by 3 months. Results: The heterotopic bone formation was found to impinge on the quadriceps mechanism, limiting knee flexion but not preventing full extension. Conservative management involving physiotherapy and analgesics was pursued, and surgical excision was avoided initially. Over 1 year, the patient showed improvement in extension, although no significant improvement in flexion was observed. Surgical excision of the heterotopic bone was performed at the end of 1 year, followed by post-operative radiotherapy to prevent recurrence. Conclusion: This case underscores the rarity of HO following TKR, particularly when it involves the quadriceps mechanism. It highlights the importance of early detection, close monitoring, and a stepwise treatment approach - starting with conservative therapy and escalating to surgical intervention when necessary. Post-operative radiotherapy can be considered in select cases to minimize recurrence.

Indexed as

conservative managementHeterotopic ossificationknee stiffnessquadriceps mechanismradiotherapysurgical excisiontotal knee replacement

Identifiers

PMID40936874
PMCPMC12422689

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