Evidence map›Paper›PMID 40936784›Full record

ArticleGastroenterology and hepatology from bed to bench2025

Comparison of success rates in intussusception reduction in children: colonoscopy versus ultrasound-guided saline enema.

Reyhaneh Naghizadeh, Ahmad Ali Davar, Alireza Teimouri, Manijeh Khalili, Mohadeseh Zadehmir

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Article in Gastroenterology and hepatology from bed to bench, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Reyhaneh NaghizadehDepartment of Radiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Ahmad Ali DavarDepartment of Radiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Alireza Teimouri2Children and Adolescents Health Research Center, Research Institute of Cellular and Molecular Science in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran.
Manijeh Khalili2Children and Adolescents Health Research Center, Research Institute of Cellular and Molecular Science in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran.
Mohadeseh ZadehmirDepartment of Radiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study evaluated and compared the success rates of intussusception reduction in children younger under three years of age using colonoscopy versus ultrasound-guided saline enema. Background: Intussusception involves telescoping one segment of the intestine into another. Methods: This experimental study included 41 children under three years old who were diagnosed with intussusception via ultrasound and admitted for reduction treatment. Participants were randomly assigned to either the saline enema or colonoscopy intervention. Data analysis was conducted using Chi-square tests and independent T-tests, utilizing SPSS 23. Results: Among the 41 children, 16 underwent reduction via colonoscopy, achieving a success rate of 81.25% (13 out of 16). In contrast, the saline enema method demonstrated a success rate of 84% (21 out of 25). The difference in success rates between the two methods was not statistically significant. Factors such as gender, age, the location of intussusception (ileocolic vs. colocolic), and the size of the intussusception did not significantly influence the success rates for either approach. Notably, intra-abdominal free fluid was significantly associated with reduced success rates for the saline enema method (P = 0.044). At the same time, no such association was found for the colonoscopy method (P = 0.142). Additionally, the presence of lymphadenopathy between the invaginated segments significantly impacted the success of the saline enema method (P = 0.036) but did not affect colonoscopy outcomes (P = 0.375). Conclusion: The study concluded that there was no significant difference in the success rates of intussusception reductions between the colonoscopy and saline enema methods. Lymph nodes between invaginated loops and intraperitoneal fluid significantly decrease the success rate of saline enema reductions, suggesting that colonoscopy may be preferable in such cases.

Indexed as

ColonoscopyIntussusceptionReductionUltrasound-guided saline enema

Identifiers

PMID40936784
PMCPMC12421923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.