ArticleJournal of biomedical optics2025
Quantifying age and spatial variations of bone marrow elasticity with noncontact optical coherence elastography.
Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Editorial: Advances in Optical Elastography.Journal of biomedical optics · 2025Article
- Optical coherence elastography detects increased corneal stiffness in nonhuman primates with experimental glaucoma.Journal of biomedical optics · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
Significance: The bone marrow is essential in immune regulation to maintain body homeostasis and to control the trafficking of stromal cells. A framework of connective tissue upholds bone marrow cells to maintain their mechanical and functional integrity. The biomechanical characterization of the bone marrow may provide useful insights for diagnosing hematologic diseases such as primary myelofibrosis. Optical coherence elastography (OCE) can measure the mechanical properties of tissues with high spatiotemporal resolution and may be well-suited for characterizing bone marrow elasticity. Aim: We demonstrate the quantification of the elastic modulus of bone marrow Approach: The femur bone marrow of CD1 mice, Results: The results show that the stiffness of femoral bone marrow increases significantly with age ( Conclusions: These findings show that OCE is promising for mapping the stiffness of the intact bone marrow and could be used for minimally invasive clinical applications.
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