Evidence map›Paper›PMID 40936732›Full record

ArticleClinical interventions in aging2025

Delayed Cholecystectomy After ERCP in Geriatric Patients: Balancing Surgical Risk and Recurrence Prevention - A Retrospective Study.

Wannakorn Prapasajchavet, Vichit Viriyaroj, Hariruk Yodying, Thammanij Rookkachart, Suun Sathornviriyapong, Thana Boonsinsukh

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Article in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Wannakorn PrapasajchavetDepartment of Surgery, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.
Vichit ViriyarojDepartment of Surgery, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.
Hariruk YodyingDepartment of Surgery, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.
Thammanij RookkachartDepartment of Surgery, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.
Suun SathornviriyapongDepartment of Surgery, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.
Thana BoonsinsukhDepartment of Surgery, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.ORCID 0000-0003-1438-9347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Laparoscopic cholecystectomy (LC) is commonly recommended following endoscopic retrograde cholangiopancreatography (ERCP) to reduce the risk of recurrent biliary events (RBE). However, in geriatric patients, this strategy remains controversial due to increased surgical risk, comorbid conditions, and decreased physiologic reserve. This study aimed to evaluate the outcomes of delayed LC in geriatric patients after ERCP for bile duct stone removal, emphasizing the role of individualized treatment planning. Methods: We retrospectively reviewed medical records of patients aged ≥75 years who underwent ERCP at Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University, from January 2018 to December 2023. Patients were grouped based on whether they underwent delayed LC (>6 weeks post-ERCP). Clinical characteristics, RBE incidence, and mortality were analyzed. Multivariate logistic regression was used to identify predictors of RBE. Results: Of 152 geriatric patients (mean age 82.3 years; 48% male), 53.3% had an ASA score ≥3, and the mean Charlson Comorbidity Index was 4.8. Delayed LC was performed in 34.2% of patients. RBE occurred in 8.6% overall, with a median onset of 390 days. The incidence of RBE was significantly lower in patients who underwent delayed LC compared with those managed without surgery (3.8% vs 11.0%, Conclusion: Subsequent LC should be considered in geriatric patients to reduce the risk of RBE after ERCP. However, given the low rates of RBE and mortality observed, a wait-and-see strategy may be a reasonable alternative in selected high-risk patients. Treatment decisions should be individualized, considering each patient's comorbidities, surgical risk, and overall health status.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholecystectomy, LaparoscopicGallstonesSecondary PreventionAgedAged, 80 and overFemaleHumansMalePostoperative ComplicationsRecurrenceRetrospective StudiesRisk FactorsTime Factorsbile duct stone removaldelayed cholecystectomygeriatric patientsrecurrent biliary eventsshared decision-making

Identifiers

PMID40936732
PMCPMC12422123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.