ReviewSports medicine and health science2025
Effects of amount, intensity, and mode of exercise training on the metabolic syndrome: A narrative review.
Review in Sports medicine and health science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Lasting Legacy: Long-Term Effects of Exercise Training on Cardiometabolic Health in the STRRIDE-Prediabetes Reunion Study.medRxiv : the preprint server for health sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Purpose: The purpose of this narrative review is to: 1) summarize findings from the three Studies of a Targeted Risk Reduction Intervention through Defined Exercise (STRRIDE) randomized trials regarding the differential effects of exercise amount, intensity, and mode on metabolic syndrome (MetS); and 2) compare the STRRIDE findings with other published randomized exercise trials related to changes in MetS. Methods: A literature review was performed to investigate the effects of exercise on composite measures of MetS. PubMed was searched between October 2023 and December 2023. To be included in this review, studies must have employed a randomized study design, whereby exercise amount, intensity, or mode was varied. Results: Findings from the STRRIDE trials and other randomized exercise trials suggest: 1) there is a relationship between exercise energy expenditure (ExEE) and improvements in composite measures of MetS; 2) there may be an asymptotic effect for ExEE beyond which further improvements in MetS are negligible or counterproductive; 3) improvements in composite measures of MetS are closely linked to insulin sensitivity; and 4) without controlling for total ExEE, combined aerobic and resistance training interventions offer the most robust improvements for composite MetS outcomes compared to either mode alone. Conclusion: Additional, large-scale, randomized exercise trials should be designed to investigate the potential asymptotic effect and associated threshold for ExEE, the interaction between exercise intensity and baseline insulin sensitivity, and the independent effects of exercise mode on MetS.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.