Evidence map›Paper›PMID 40936639›Full record

ArticleHealth SA = SA Gesondheid2025

A systematic review on factors influencing immunisation adherence among children under 12 years of age.

Bridgette Lockett, Juliana J Willemse, Rugira M Modeste

Abstract read
In one paragraph

Article in Health SA = SA Gesondheid, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bridgette LockettSchool of Nursing, Faculty of Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-9095-6764
Juliana J WillemseSchool of Nursing, Faculty of Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-5196-7401
Rugira M ModesteDepartment of Nursing and Midwifery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-0329-3526

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Immunisation is crucial for preventing the spread of infectious diseases; yet, adherence remains a global challenge, particularly among children under 12. Understanding the multifaceted factors influencing vaccination adherence is essential for improving coverage rates and reducing the burden of vaccine-preventable diseases. Aim: This study aimed to develop a support intervention for improvement in childhood immunisation adherence in South Africa. Methods: Following the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, a comprehensive search was conducted across multiple databases. The Patient (problem or population); Intervention; Comparison, control or comparator and Outcome(s) framework guided the research question formulation and search strategy. Included studies were published between 2013 and 2023, focusing on children under 12. Data were extracted and categorised into domains affecting immunisation adherence. Quality assessment was performed using the mixed methods appraisal tool. Results: The review identified five major domains influencing immunisation adherence: socioeconomic factors, health system factors, vaccine beliefs and attitudes, cultural and social factors, and communication and information factors. Conclusion: This review highlights the complex interplay of factors affecting childhood vaccination adherence. Critical areas for intervention include tailored communication strategies, addressing vaccine hesitancy, enhancing immunisation accessibility and leveraging digital technologies for vaccine promotion. Contribution: These insights can guide evidence-based strategies to improve immunisation adherence and inform policy in the evolving landscape of global public health.

Indexed as

adherencechildrenhealth systemsimmunisationsocioeconomic factorsvaccine hesitancy

Identifiers

PMID40936639
PMCPMC12421498

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.