Evidence map›Paper›PMID 40936511›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Collagen Use in Periorbital Rejuvenation for Chinese Patients: The Restoration Injection for Optimal Rejuvenation Technique.

Qingyu Hao, Wenrong Tian, Huinan Chang, Jiang Ai

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Operational Standard for Tissue-Extracted Collagen Facial Injection Techniques.Clinical, cosmetic and investigational dermatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qingyu HaoFrom the Department of Plastic Surgery, Jinshi Medical Aesthetics Hospital, Shanghai, China.
Wenrong TianDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Huinan ChangDepartment of Plastic Surgery, Shanmei Outpatient Clinic, Taiyuan, China.
Jiang AiDepartment of Plastic Surgery, Yibeijia Outpatient Clinic, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern periorbital rejuvenation treatments involve a comparison of various injectable materials to optimize therapeutic outcomes. This article highlights the advantages of collagen in periorbital rejuvenation and introduces the restoration injection for optimal rejuvenation (RIO) technique as a precise and safe injection method. Due to the complex anatomical and physiological characteristics of the periorbital area, conventional injectable materials may lead to adverse reactions or suboptimal results. Collagen, however, offers excellent adhesion and minimal migration, and effectively improves both pigmented and structural dark circles. To ensure long-term results and minimize complications, the RIO technique, developed based on the authors' years of injection experience, optimizes collagen application. This low-cost technique is suitable for personalized customization, is safe and effective, and provides patients with a reliable periorbital rejuvenation solution.

Identifiers

PMID40936511
PMCPMC12422767

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.