Evidence map›Paper›PMID 40936497›Full record

ArticleGlobal health action2025

Dispensing of medicines for asthma and chronic obstructive pulmonary disease through the government health insurance in Syria: a retrospective analysis.

Saleh Aljadeeah, Raffaella Ravinetto, Ana Tomas

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Article in Global health action, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Saleh AljadeeahDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0003-4035-4121
Raffaella RavinettoDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-7765-2443
Ana TomasDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.ORCID 0000-0003-2361-872X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma and chronic obstructive pulmonary disease (COPD) are common noncommunicable diseases, exacerbated in conflict settings by the heightened environmental exposure to triggers, weakened health systems, and poor access to medicines and healthcare. However, accurate data on medicines dispensing in this context are generally scarce.

objectiveWe examined the patterns and rates of medicines dispensing for asthma and COPD among the beneficiaries of the Syrian governmental health insurance scheme between June 2018 and March 2021.

methodsWe retrospectively analyzed the outpatient dispensing records for 125,371 adults. Medicines for asthma and COPD were identified using the Anatomical Therapeutic Chemical (ATC) classification system. Dispensing rates were calculated as the number of packages per 1,000 beneficiaries per month, stratified by age, sex, and route of administration.

resultsOut of our sample, 15.02% received at least one package of a medicine for asthma or COPD. Oral formulations were the most frequently dispensed (92.67% of patients), particularly oral salbutamol and xanthines. Inhaled medicines, including inhaled corticosteroids (ICS) and ICS long-acting β2-agonists (ICS-LABA) combinations, were markedly under-dispensed (17.08% of patients). Dispensing rates were higher in females and older adults. Seasonal variation showed peaks in autumn and winter, with a notable decline in April 2020, coinciding with the early COVID-19 period.

conclusionsThe study highlights substantial gaps in dispensing of medicines for asthma and COPD, with particularly low rates for inhalers, likely reflecting barriers driven by the conflict, economic instability, and sanctions. Robust coordinated action is needed to improve their availability in Syria.

Indexed as

Anti-Asthmatic AgentsAsthmaInsurance, HealthPulmonary Disease, Chronic ObstructiveAdolescentAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSyriaYoung AdultAnti-Asthmatic AgentsAccess to medicinesconflict settingprimary health careQuality of Care for Chronic Conditionsrespiratory diseasessanctions

Identifiers

PMID40936497
PMCPMC12434846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.