Evidence map›Paper›PMID 40936430›Full record

ArticleGM crops & food2025

Relative safety of glyphosate-resistant maize (CC-2) in rats.

Anyi Liu, Xueqian Yin, Jing Wen, Chao Hou, Ruoyu Zhou, Xinran Liu, Ning Yin, Yuanzhi Jian, Shan Liu, Xiaoxuan Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GM crops & food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anyi LiuDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Xueqian YinDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Jing WenDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Chao HouDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Ruoyu ZhouDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Xinran LiuDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Ning YinDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Yuanzhi JianDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Shan LiuKey Laboratory of Food Safety Risk Assessment of Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing, China.
Xiaoxuan ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
Junbo WangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rapid adoption of glyphosate-resistant (GR) crops by farmers, the food safety has garnered significant attention. This study aims to evaluate the relative safety of glyphosate-resistant maize (CC-2). Rats were divided into three groups: one group receiving AIN-93 G feed (AIN), one receiving non-modified receptor maize feed (NM), and the other receiving CC-2 maize feed (GM). The intervention spanned from gestation d 0 of the parental rats to 90 d post-weaning of the offspring. The results indicated no significant differences in pregnancy outcomes, body weight, growth monitoring, behavioral tests, or organ indexes between the GM group and the two control groups (AIN and NM). Although there were significant differences in some hematological parameters, serum chemistry, and organ weights, histopathological analysis revealed no abnormalities. No exogenous gene fragments were detected in major organs. In conclusion, CC-2 maize is relative safe for growth and development in rats.

Indexed as

GlycineHerbicide ResistancePlants, Genetically ModifiedZea maysAnimal FeedAnimalsFemaleFood SafetyGlyphosateHerbicidesMalePregnancyRatsGlycineGlyphosateHerbicidesgenetically modifiedGlyphosate-Resistant Maize

Identifiers

PMID40936430
PMCPMC12439554

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.