Evidence map›Paper›PMID 40936341›Full record

ArticlePsychological medicine2025

Interpersonal and targeted rejection life stressors are proximal risk factors for suicidal ideation and behavior.

Lori N Scott, Iulia Banica Malcolm, Sarah L Brown, Evelyn M Hernandez Valencia, Robert T Krafty, George M Slavich

Abstract read
In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lori N ScottDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-5238-876X
Iulia Banica MalcolmOntario Shores Centre for Mental Health Sciences, Whitby, ON, Canada.ORCID 0000-0001-8816-3012
Sarah L BrownDepartment of Psychology, https://ror.org/05g3dte14Florida State University, Tallahassee, FL, USA.ORCID 0000-0001-6712-4436
Evelyn M Hernandez ValenciaDepartment of Psychology, https://ror.org/013ckk937University of Rhode Island, Kingston, RI, USA.ORCID 0009-0009-0207-3522
Robert T KraftyDepartment of Biostatistics and Bioinformatics, https://ror.org/03czfpz43Emory University, Atlanta, GA, USA.ORCID 0000-0003-1478-6430
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, https://ror.org/046rm7j60University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-5710-3818

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Multimodal Assessment of Near-term Risk Processes for Suicide Ideation and BehaviorR01MH115922 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Lori N Scott · 2019 to 2026
$4.3M
Causal Mechanisms Underlying Social Pain and Suicidal Behaviors: Examining the Role of Altered Decision-making and Psychophysiological ReactivityF32MH126527 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROWN, SARAH LOUISE · 2022 to 2024
$180k
NCATS NIH HHS UL1 TR001857NIMH NIH HHS F32 MH126527NIMH NIH HHS R01 MH115922NIMH NIH HHS UL1TR001857
6 · The paper itself

Abstract

backgroundAlthough life stressors are known risk factors for suicide, the specific stressor types that most strongly precipitate suicidal outcomes, and on what timescale, remain poorly understood. Based on existing theory, we investigated whether objectively rated interpersonal stressors, especially social and targeted rejection stressors, are proximally associated with increased likelihood of suicidal ideation and behavior.

methodUsing an objectively rated contextual threat interview to assess stressful life events, and a timeline followback procedure for assessing suicide-related outcomes, we examined how the severity of four types of acute life events (i.e. non-interpersonal, interpersonal without social rejection, social rejection without targeted rejection, and targeted rejection) were temporally associated with the likelihood of same-day and next-day suicidal ideation and behavior over 16 months in 143 young adults (

resultsAfter controlling for prior-day suicidal ideation and non-interpersonal stressors, daily within-person increases in interpersonal stressor severity were related to higher odds of same-day (but not next-day) suicidal ideation. Additionally, greater increases in targeted rejection severity were uniquely related to increased likelihood of both same-day and next-day suicidal behavior after controlling for prior-day suicidal behavior and other types of stressors.

conclusionsInterpersonal stressors are strong, proximal risk factors for suicidal ideation and behavior, and these effects are particularly strong for targeted rejection life events. Clinicians should thus assess recent interpersonal and, especially, targeted rejection stressors when evaluating acute suicide risk, and may reduce such risk by helping patients stabilize and strengthen their social relationships.

Indexed as

Interpersonal RelationsLife Change EventsPsychological DistanceStress, PsychologicalSuicidal IdeationAdultFemaleHumansMaleRisk FactorsYoung Adultinterpersonal stresslife eventssuicidal behaviorsuicidal ideationtargeted rejection

Identifiers

PMID40936341
PMCPMC12517110

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.