Evidence map›Paper›PMID 40936034›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Oral rehabilitation and quality of life in head and neck cancer patients receiving dental clearance prior to radiotherapy: a retrospective observational study.

Matthijs In 't Veld, Frank K J Leusink, Chayenne N Chhangur, Naichuan Su, Femke Jansen, Marije R Vergeer, Irma M Verdonck-de Leeuw, Engelbert A J M Schulten

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthijs In 't VeldDepartment of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. m.intveld@amsterdamumc.nl.
Frank K J LeusinkDepartment of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Chayenne N ChhangurDepartment of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Naichuan SuDepartment of Oral Public Health, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands.
Femke JansenDepartment Otolaryngology-Head and Neck Surgery, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Marije R VergeerDepartment of Radiation Oncology, Amsterdam UMC, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Irma M Verdonck-de LeeuwDepartment Otolaryngology-Head and Neck Surgery, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Engelbert A J M SchultenDepartment of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis retrospective observational study examined oral rehabilitation and the total oral rehabilitation time (TORT) in head and neck cancer patients (HNC) who underwent full dental clearance before intensity-modulated radiotherapy (IMRT). Additionally, it assessed changes in health-related quality of life (HRQoL) before and after IMRT and oral rehabilitation.

methodsHNC patients with HRQol data who underwent full dental clearance before IMRT in Amsterdam UMC between 2008 and 2021 were included. The EORTC QLQ-C30 and QLQ-H&N35 were used to assess HRQoL before dental clearance at baseline (T

resultsHRQoL data were available for 28 patients at T

conclusionAll HNC patients in this study underwent dental clearance before IMRT and received oral rehabilitation with conventional dentures, with a mean TORT of over a year. Patients after oral rehabilitation had less oral pain but more problems with teeth and finances. Large prospective cohort studies are needed to confirm these findings.

Indexed as

Head and Neck NeoplasmsMouth RehabilitationQuality of LifeRadiotherapy, Intensity-ModulatedAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTime FactorsHead and neck cancerOral cancerOral rehabilitationQuality of life

Identifiers

PMID40936034
PMCPMC12426075

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.