Evidence map›Paper›PMID 40935892›Full record

ArticleAnnals of surgical oncology2025

Association Between Intraoperative Hypothermia and Postoperative Pancreatic Fistula.

Maho Takayama, Rebecca A Snyder, Heather G Lyu, Cassius K Mensah, Laura R Prakash, Jace P Landry, Edward Tsai, Zuhair A Siddiqui, Jessica E Maxwell, Michael P Kim and 4 more

Abstract read
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Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Maho TakayamaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Rebecca A SnyderDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Heather G LyuDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cassius K MensahDepartment of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Laura R PrakashDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jace P LandryDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Edward TsaiDepartment of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zuhair A SiddiquiDepartment of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jessica E MaxwellDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael P KimDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ching-Wei D TzengDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jeffrey E LeeDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Matthew H G KatzDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Naruhiko IkomaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. nikoma@mdanderson.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypothermia frequently occurs during abdominal operations and negatively impacts postoperative outcomes. However, the association of hypothermia during pancreaticoduodenectomy (PD) with postoperative pancreatic fistula (POPF) remains unclear.

methodsThis retrospective study analyzed data from patients who underwent open PD at our institution from January 2018 through March 2024. Data on patient demographics, tumor characteristics, surgical outcomes (including POPF), and intraoperative temperature were collected. We sought to determine the incidence of intraoperative hypothermia, defined as an intraoperative core temperature below 36.0 °C, and investigated its association with POPF using multivariable logistic regression models.

resultsAmong 374 patients, 293 (78.3%) experienced hypothermia and 36 (9.6%) developed clinically relevant POPF. Multivariable analysis revealed that age ≥ 55 years (odds ratio [OR] 2.2; 95% confidence interval [CI] 1.2-4.0; p = 0.012) and operative time ≥ 435 min (OR 2.5; 95% CI 1.4-4.2; p = 0.001) were associated with increased incidence of hypothermia, while body mass index ≥ 25 kg/m

conclusionsAmong patients undergoing open PD, hypothermia is common and is associated with increased risk for POPF. Further studies are needed to establish a validated and standardized definition of intraoperative hypothermia and to examine any associations with procedure-specific postoperative complications.

Indexed as

HypothermiaIntraoperative ComplicationsPancreatic FistulaPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsAgedFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedOperative TimePrognosisRetrospective StudiesHypothermiaIntraoperative temperaturePancreaticoduodenectomyPostoperative complicationsPostoperative pancreatic fistula

Identifiers

PMID40935892

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