ReviewSeminars in radiation oncology2025
Intraoperative Radiation for Pancreatic Cancer.
Review in Seminars in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Pancreatic cancer (PDAC) remains a challenging disease to treat with a poor prognosis. Management of PDAC has evolved over the last several decades with the development of more effective systemic therapy making local control of the primary tumor paramount in patients with both resectable and unresectable disease. Local recurrence after resection or progression of an unresectable tumor are significant causes of morbidity and potential mortality for patients with PDAC. Emerging data in PDAC suggest that improved local control and favorable survival can be achieved with radiation dose escalation. However, adjacent radiosensitive organs limit the ability to deliver higher doses of radiation therapy to patients. Intraoperative radiation therapy provides an ideal way to deliver large doses of radiation directly to the tumor or tumor bed while minimizing the radiation dose to adjacent normal organs. The purpose of this review is to provide an overview of the current literature demonstrating the utility of intraoperative radiation therapy in patients with resectable and unresectable PDAC.
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Registered trials
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