Evidence map›Paper›PMID 40934365›Full record

ArticleAntimicrobial agents and chemotherapy2025

Incorporation of macrophage immune stresses into an intracellular assay of drug tolerance in

Greana Kirubakar, Luana Johnston, Bom Nae Rin Lee, David G Russell, Nelson V Simwela

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Greana KirubakarDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Luana JohnstonDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Bom Nae Rin LeeDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
David G RussellDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-9748-750X
Nelson V SimwelaDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

Funding

Systems Biology CoreU19AI162598 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI SALGAME, PADMINI · 2021 to 2025
$13.9M
Lung immune function in human TB infection and its perturbation by HIV-1.R01AI155319 · NIAID · CORNELL UNIVERSITY · PI MWANDUMBA, HENRY CHARLES, RUSSELL, DAVID G · 2020 to 2024
$3.3M
BSL3 Flow Sorter for Human Pathogens of Global SignificanceS10OD032135 · OD · CORNELL UNIVERSITY · PI RUSSELL, DAVID G · 2022 to 2022
$362k
Bill and Melinda Gates Foundation INV-079192National Institute of Allergy and Infectious Diseases AI155319National Institute of Allergy and Infectious Diseases AI162598NIAID NIH HHS R01 AI155319NIAID NIH HHS U19 AI162598NIH HHS S10 OD032135ODCDC CDC HHS OD032135
6 · The paper itself

Abstract

Development of new and improved tuberculosis (TB) chemotherapies is hampered by antibiotic resistance and drug tolerance by

Indexed as

Antitubercular AgentsDrug ToleranceMacrophagesMycobacterium tuberculosisAnimalsMiceMicrobial Sensitivity TestsAntitubercular Agentsdrug discoverydrug tolerancehost-directed therapeuticsmacrophageMycobacterium tuberculosis

Identifiers

PMID40934365
PMCPMC12486812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.