Evidence map›Paper›PMID 40934103›Full record

ArticleeLife2025

Xcr1

Tianhan Li, Liaoxun Lu, Juanjuan Qiu, Xin Dong, Le Yang, Kexin He, Yanrong Gu, Binhui Zhou, Tingting Jia, Toby Lawrence and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Xcr1eLife · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tianhan Li *School of Basic Medicine, Xinxiang Medical University, Xinxiang, China.
Liaoxun Lu *School of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Juanjuan QiuSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Xin DongSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Le YangSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Kexin HeSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Yanrong GuSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Binhui ZhouSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Tingting JiaSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Toby LawrenceCentre d'Immunologie de Marseille-Luminy, INSERM, CNRS, Aix-Marseille Université, Marseille, France.
Marie MalissenCentre d'Immunologie de Marseille-Luminy, INSERM, CNRS, Aix-Marseille Université, Marseille, France.
Guixue WangKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China.
Rong HuangSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Hui WangSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.
Bernard MalissenCentre d'Immunologie de Marseille-Luminy, INSERM, CNRS, Aix-Marseille Université, Marseille, France.ORCID https://orcid.org/0000-0003-1340-9342
Yinming LiangSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.ORCID https://orcid.org/0000-0001-9174-4037
Lichen ZhangSchool of Medical Technology, Xinxiang Medical University, Xinxiang, China.ORCID https://orcid.org/0000-0002-7810-9941

Funding

National Natural Science Foundation of China 32170879National Natural Science Foundation of China 82301972Science and Technology Department of Henan Province 242102310030Science and Technology Innovation Program of Hunan Province 2022RC1223Science and Technology Innovation Program of Hunan Province 2023DK2005Science and Technology Innovation Program of Hunan Province 2024RC1071
6 · The paper itself

Abstract

Atherosclerosis is characterized by lipid accumulation within plaques, leading to foam cell formation and an inflammatory response within the aortic lesions. Lipid disorders have been extensively investigated, however, the cellular and molecular mechanisms that trigger the inflammatory response in atherosclerotic plaques remain far from being fully understood. Xcr1

Indexed as

AtherosclerosisDendritic CellsAnimalsDisease Models, AnimalDisease ProgressionHumansMaleMiceMice, Inbred C57BLPlaque, AtheroscleroticReceptors, ChemokineReceptors, ChemokineXC chemokine receptor 1, mouseatherosclerosiscDC1immunologyinflammationmouseXcl1Xcr1

Identifiers

PMID40934103
PMCPMC12425476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.