Evidence map›Paper›PMID 40933969›Full record

ArticleTurkish journal of medical sciences2025

Comparison of novel DiaRD-HBV DNA qPCR kit with the

Ülker Çuhaci, Hande Toptan, Bengül Durmaz, Mehmet Köroğlu, Rıza Durmaz

Abstract readComparative Study
In one paragraph

Article in Turkish journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ülker ÇuhaciDepartment of Medical Microbiology, Faculty of Medicine, Yüksek İhtisas University, Ankara, Turkiye.ORCID https://orcid.org/0000-0002-6420-6185
Hande ToptanDepartment of Medical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkiye.ORCID https://orcid.org/0000-0001-6893-8490
Bengül DurmazDepartment of Medical Microbiology, Faculty of Medicine, Lokman Hekim University, Ankara, Turkiye.ORCID https://orcid.org/0000-0002-9093-7440
Mehmet KöroğluDepartment of Medical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkiye.ORCID https://orcid.org/0000-0001-8101-1104
Rıza DurmazDepartment of Medical Microbiology, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkiye.ORCID https://orcid.org/0000-0001-6561-778X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Hepatitis B virus (HBV) leads to widespread chronic infections that may result in long-term complications such as cirrhosis and hepatocellular carcinoma. The use of sensitive molecular methods for HBV DNA quantitation has provided significant contributions for diagnosis and monitoring of disease. The current study aimed to evaluate the diagnostic performances of a novel DiaRD HBV qPCR kit (novel kit) in comparison with the Materials and methods: A total of 288 plasma samples-105 HBV DNA-positive and 183 HBV DNA-negative-were tested using both kits. The diagnostic and quantitative results of the novel kit were compared to those of the comparator kit. Results: The novel kit had very high sensitivity, specificity, and accuracy with rates of >99.9%. Comparative analyses conducted on 105 HBV DNA-positive samples showed no significant differences of ≥ 1 log Conclusion: The result of the current study indicates that this novel DiaRD HBV qPCR kit can be used in routine diagnosis and monitoring of HBV infections.

Indexed as

DNA, ViralHepatitis BHepatitis B virusReagent Kits, DiagnosticReal-Time Polymerase Chain ReactionHumansMaleReproducibility of ResultsSensitivity and SpecificityViral LoadDNA, ViralReagent Kits, Diagnosticartus HBV QS-RGQ kitDiaRD-HBV qPCR kitHepatitis B virusnovel kit

Identifiers

PMID40933969
PMCPMC12419036

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.