Evidence map›Paper›PMID 40933904›Full record

ArticleCureus2025

Appendiceal Diverticulitis Masquerading as Perforated Acute Appendicitis: Diagnostic Pitfalls With a Potential Computed Tomography Radiologic Clue.

Shivam Gandhi, Gustav A Blomquist, Andrew J Weaver, Krista L Denning, John Diks

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shivam GandhiGastroenterology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Gustav A BlomquistRadiology, University of Kentucky College of Medicine, Lexington, USA.
Andrew J WeaverTrauma and Surgical Critical Care, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Krista L DenningPathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
John DiksPathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 50-year-old man presenting with acute right lower quadrant pain and leukocytosis. Computed tomography suggested acute appendicitis with possible microperforation. Laparoscopic appendectomy revealed diverticulum-like outpouchings, and histopathology confirmed acute appendiceal diverticulitis with periappendicitis. Appendiceal diverticulitis is an uncommon but clinically significant entity due to its increased risk of perforation and possible association with neoplasia. The clinical and radiologic findings often mimic acute appendicitis, leading to under-recognition without careful review. In our case, a small gas locule seen on CT, initially interpreted as a microperforation, was retrospectively identified as a diverticulum. This finding highlights the potential diagnostic value of intramural gas micro-loculations and a saccular appendiceal contour on CT, particularly when combined with asymmetric periappendiceal fat stranding and wall thickening. Awareness of these imaging features may aid in distinguishing appendiceal diverticulitis from routine appendicitis, prompting appropriate surgical management and histopathologic assessment. Recognition of this condition is important for timely treatment and for guiding follow-up, given the associated risks.

Indexed as

acute appendicitisappendiceal diverticulitisct radiological signgas micro-loculationmicroperforation

Identifiers

PMID40933904
PMCPMC12418721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.