ArticleDEN open2026
Utility of the Endoscopic Pressure Study Integrated System in Identifying Silent Gastroesophageal Reflux Disease During Routine Health Check-ups.
Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
13 authors.
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Abstract
Objectives: The endoscopic pressure study integrated system (EPSIS) is a novel functional endoscopic modality that records intragastric pressure (IGP) waveforms during CO Methods: We retrospectively analyzed 185 participants who underwent esophagogastroduodenoscopy (EGD) and EPSIS as part of routine health check-ups at a single center between November 2024 and March 2025. Participants were classified into erosive and non-erosive groups based on the presence or absence of mucosal breaks (Grade A or higher) according to the Los Angeles classification. Background characteristics, EPSIS parameters, and endoscopic findings were compared. Results: EPSIS was safely performed in all participants without adverse events. The erosive esophagitis group showed significantly more flat waveform patterns (39.4% vs. 14.5%, Conclusion: EPSIS enables a safe and objective assessment of LES function and may support the identification of erosive esophagitis in asymptomatic individuals. It may hold promise as a functional diagnostic tool for the detection of silent GERD and may support preventive strategies during routine endoscopy.
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