Evidence map›Paper›PMID 40933869›Full record

ArticleAnimal reproduction2025

Advances in ovarian follicle culture systems: exploring the interplay between cells, matrix, and ovarian architecture.

Alberto Maria Luciano, Noemi Monferini, Ludovica Donadini, Pritha Dey, Fernanda Fagali Franchi, Valentina Lodde, Federica Franciosi

Abstract read
In one paragraph

Article in Animal reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dynamic Remodeling of Oocyte-Granulosa Cell Communication During Bovine Folliculogenesis Revealed by Transcriptomic Meta-Analyses.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Approaches toAnimal reproduction · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alberto Maria LucianoReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0000-0002-8016-9919
Noemi MonferiniReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0000-0002-2339-9953
Ludovica DonadiniReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0009-0005-9258-9047
Pritha DeyReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0000-0002-1601-6379
Fernanda Fagali FranchiReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0000-0002-9859-0576
Valentina LoddeReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0000-0002-9768-2292
Federica FranciosiReproductive and Developmental Biology Laboratory - ReDBioLab, Department of Veterinary Medicine and Animal Sciences, University of Milan, Milan, Italy.ORCID 0000-0001-8742-0291

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to develop oocytes from the earliest follicular stages through maturation and fertilization in vitro would revolutionize fertility preservation in human medicine and animal breeding. Instead, current assisted reproductive technologies rely only on a limited portion of the female gamete reserve, corresponding to the antral population, while the preantral follicle reserve remains unexploited, mainly due to a lack of knowledge regarding the mechanisms that guide preantral follicle differentiation and folliculogenesis in vitro. This review highlights the efforts made thus far and suggests an approach to studying the mechanisms and ovarian environment to enhance preantral follicle culture systems.

Indexed as

3Dculture systemovarypreantral folliclesscaffold

Identifiers

PMID40933869
PMCPMC12419246

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.