Evidence map›Paper›PMID 40933844›Full record

ArticleProceedings. IEEE International Conference on Bioinformatics and Biomedicine2024

An application of studying FAERS data to Enhance Drug Safety and Treatment Outcomes in Rare Diseases.

Jaber Valinejad, Yanji Xu, Qian Zhu

Abstract read
In one paragraph

Article in Proceedings. IEEE International Conference on Bioinformatics and Biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jaber ValinejadDivision of Preclinical Innovations, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, USA.
Yanji XuDivision of Rare Disease Research Innovations, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, USA.
Qian ZhuDivision of Preclinical Innovations, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, USA.

Funding

Informatics Research CoreZIATR000410 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI MATHE, EWY · 2020 to 2020
$595k
Intramural NIH HHS Z99 TR999999Intramural NIH HHS ZIA TR000410
6 · The paper itself

Abstract

Rare diseases affect fewer than 200,000 individuals in the United States, with some being so rare that only a handful of people are impacted. According to the U.S. Food and Drug Administration (FDA), there are 1,268 approved orphan drugs available for treating these conditions. However, potentially beneficial drugs can also have side effects. Some adverse events, while serious, may be rare, making them difficult to identify or quantify in randomized controlled trials. Understanding these events is critical for improving patient safety and treatment outcomes. To better assess these risks, we aimed at summarizing adverse drug events for rare diseases by utilizing FDA Adverse Event Reporting System (FAERS). This study offers a foundation for future research of improving drug safety in rare diseases.

Indexed as

adverse drug eventFAERSknowledge graphRare disease

Identifiers

PMID40933844
PMCPMC12419809

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.