ArticleNeurotrauma reports2025
Redirection of Care after Traumatic Brain Injury in Intensive Care: Sex and Social Determinants of Health.
Article in Neurotrauma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Sex-related differences in end-of-life decision-making in patients with traumatic brain injury: a systematic review and meta-analysis.BMC palliative care · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic brain injury (TBI) impairs a patient's capacity for informed decision-making, necessitating surrogate decision-makers to decide whether to continue life-sustaining therapies. Patient sex and social determinants of health (SDH)-for example, economic stability, education, and health care access-possibly affect such decisions. We aimed to explore interactions between sex, SDH, and redirection of care in a cohort of patients with TBI from a high-income, high-resource country. Adult patients with consecutive TBI admitted to intensive care were included. Data on demographics, TBI characteristics, advance directives, and SDH (civil status, living situation, dependence for daily activities, income, employment, religion, nationality) were extracted. The primary end-point was redirection of care, followed by in-hospital mortality. Differences were analyzed univariably, after prognostic score matching, and through random forest models to assess the importance of each factor. Seven hundred and twelve patients (26.4% female, median age 56) were included. Women were older, more often widowed, and more frequently dependent on help, while men had higher income and education levels. Redirection of care and mortality were more common in women, even after prognostic score matching, though the difference disappeared after adjusting for redirection of care. Random forest models identified employment status and dependence on support as key factors associated with redirection of care, while sex did not improve model performance. Our results underline the importance of SDH for prognostication of patients with TBI and suggest that it is not sex
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