Evidence map›Paper›PMID 40933832›Full record

ArticleNeurotrauma reports2025

Risk of Mortality Among Adult Females Diagnosed with Traumatic Brain Injury in an Academic Medical System.

Bernadette A D'Alonzo, Abigail C Bretzin, Rebecca B Morse, Silvia P Canelón, Douglas J Wiebe, Andrea L C Schneider, Mary Regina Boland

Abstract read
In one paragraph

Article in Neurotrauma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bernadette A D'AlonzoDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3760-2158
Abigail C BretzinInjury Prevention Center, Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Rebecca B MorseDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Silvia P CanelónDepartment of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Douglas J WiebeDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Andrea L C SchneiderDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-0026-5052
Mary Regina BolandInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
BRIAN INJURY TRAINING GRANTT32NS043126 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Douglas Hamilton Smith · 2003 to 2026
$5.9M
Establishing Mechanisms Between Traumatic Brain Injury and Dementia Using Epidemiology, Clinical Studies, Blood-Based Biomarkers, and Neuroimaging BiomarkersK23NS123340 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider · 2022 to 2026
$1.1M
Traumatic Brain Injury, Social Relationships, and Risk of DementiaF32AG096999 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Bernadette D'Alonzo · 2025 to 2026
$152k
NCATS NIH HHS UL1 TR001878NCIPC CDC HHS R49 CE003083NIA NIH HHS F32 AG096999NINDS NIH HHS K23 NS123340NINDS NIH HHS T32 NS043126
6 · The paper itself

Abstract

The objective of this retrospective cohort study was to evaluate mortality risk over five years among 6,432 female patients with a health care encounter diagnosis of TBI from hospitals and outpatient clinics within a university health system. We used TBI severity, defined by the Centers for Disease Control and Department of Defense/Veterans Affairs: mild, moderate/severe/penetrating, indeterminate severity. To determine patient death, we used death in a Penn Medicine facility and linkage to the Social Security Death Index. We used Cox proportional hazards models adjusted for age at the time of TBI diagnosis, race, and encounter type to estimate associations of TBI severity with mortality risk. We evaluated interactions with encounter type and age, and stratified results by inpatient/outpatient and age group (≥65 years). Median age was 47 years (25th-75th percentiles: 29-63). Patients were most commonly self-reported White race (

Indexed as

femaleslifespanmortality riskseveritytraumatic brain injury

Identifiers

PMID40933832
PMCPMC12419401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.