Evidence map›Paper›PMID 40933812›Full record

ReviewFrontiers in digital health2025

Generative AI in consumer health: leveraging large language models for health literacy and clinical safety with a digital health framework.

Annemarie K Tilton, Brian E Caplan, Brian J Cole

Abstract readReview
In one paragraph

Review in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annemarie K TiltonIndependent Researcher, Park City, UT, United States.
Brian E CaplanDepartment of Orthopaedics, Rush University Medical Center, Chicago, IL, United States.
Brian J ColeDepartment of Orthopaedics, Rush University Medical Center, Chicago, IL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generative AI, powered by large language models, is transforming consumer health by enhancing health literacy and delivering personalized health education. However, ensuring clinical safety and effectiveness requires a robust digital health framework to address risks like misinformation and inequitable communication. This mini review examines current use cases for generative AI in consumer health education, highlights persistent challenges, and proposes a clinician-informed framework to evaluate safety, usability, and effectiveness. The RECAP model-Relevance, Evidence-based, Clarity, Adaptability, and Precision-offers a pragmatic lens to guide responsible implementation of AI in patient-facing tools. By connecting insights from past digital health innovations to the opportunities and pitfalls of large language models, this paper provides both context and direction for future development.

Indexed as

AI evaluation frameworkclinical safetyconsumer health educationdigital health ethicsgenerative AIhealth literacylarge language models (LLMs)

Identifiers

PMID40933812
PMCPMC12417475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.