Evidence map›Paper›PMID 40933542›Full record

ArticleRoyal Society open science2025

Comparative study of cavitands-based nanocapsule as a drug delivery vehicle for an anti-cancer and multiple sclerosis drug-A DFT study.

Annum Ahsan, Sehrish Sarfaraz, Malai Haniti S A Hamid, Nadeem S Sheikh, Khurshid Ayub

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annum AhsanDepartment of Chemistry, COMSATS University, Abbottabad Campus, KPK, 22060, Pakistan.
Sehrish SarfarazDepartment of Chemistry, COMSATS University, Abbottabad Campus, KPK, 22060, Pakistan.
Malai Haniti S A HamidChemical Sciences, Faculty of Science, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong BE1410, Brunei Darussalam.
Nadeem S SheikhChemical Sciences, Faculty of Science, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong BE1410, Brunei Darussalam.ORCID https://orcid.org/0000-0002-0716-7562
Khurshid AyubDepartment of Chemistry, COMSATS University, Abbottabad Campus, KPK, 22060, Pakistan.ORCID https://orcid.org/0000-0003-0990-1860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoscale-assisted drug delivery systems give a platform to alter elementary properties associated with drug particles to limit their adverse effects. In this regard, deep benzimidazolone cavitand-based dimeric nanocapsule, which can act as good host for small guest molecules, is considered to be used as drug delivery vehicle. In the current study, we report the benzimidazolone cavitand-based nanocapsules as drug delivery systems for the drugs, i.e. ampyra (AM) and merceptopurine (MP) at M06-2x/6-31G(d,p) level of theory. AM and MP drugs interact with the nanocapsule with the interaction energies of -26.02 kcal mol

Indexed as

ampyrabenzimidazolonecavitand nanocapsuledrug deliverymerceptopurinequantum theory of atoms in molecules analysis

Identifiers

PMID40933542
PMCPMC12419892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.