ArticleJournal of pain research2025
Efficacy of Myofascial Trigger Point Dry Needling in Treatment of Primary Dysmenorrhea: A Study Protocol for a Three-Arm Randomized Controlled Trial.
Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06316583 (Clinical Study of Dry Needling on Myofascial Trigger Points Treatment for Primary Dysmenorrhea and Preliminary Investigation of Its Relevance to Acupoints), which is not on this map. Not yet cited in PubMed.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Study of Dry Needling on Myofascial Trigger Points Treatment for Primary Dysmenorrhea and Preliminary Investigation of Its Relevance to Acupoints
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Authors and funding
11 authors.
Funding
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Abstract
Background and Objective: Primary dysmenorrhea carries substantial medical, social, and economic burdens, leading many patients to seek low-risk complementary and alternative therapies, such as acupuncture. Myofascial trigger point dry needling (MTrP-DN) has recently gained attention as a potential treatment, though evidence remains limited and its distinction from acupuncture is debated. Therefore, this study aims to evaluate the therapeutic efficacy of MTrP-DN for primary dysmenorrhea, using traditional acupuncture as an active control and sham needling as a passive control. Methods and Analysis: This is a randomized, subject-blind, sham-controlled trial. A total of 150 subjects with primary dysmenorrhea will be randomly assigned in a 1:1:1 ratio to the MTrP-DN, acupuncture, or sham group, receiving consecutive 3-week treatments with follow-up for 12 months. The primary outcome is pain intensity, measured by the visual analogue scale (VAS). Secondary outcomes include quality of life, non-steroidal anti-inflammatory drug (NSAID) usage, self-reported improvement using the Global Rate of Change (GROC) scale, serum inflammatory markers, and uterine blood flow assessed by Doppler. Outcomes will be evaluated at baseline, 1 Discussion: This study is the first to compare the efficacy of MTrP-DN with acupuncture in the treatment of primary dysmenorrhea, focusing on their effects on pain intensity, uterine blood flow, and inflammatory markers. Including a sham control group helps address blinding issues and accurately assess MTrP-DN's effects on pain and quality of life. Trial Registration Number: Clinicaltrial.gov (NCT06316583).
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