ArticleAsia Pacific allergy2025
Exploring the relationship between menstrual cycle and urticaria: Insights from a cross-sectional study.
Article in Asia Pacific allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sex differences in innate immune cell responses: Impact on cancer immunity and response to therapy.Frontiers in immunology · 2026Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic spontaneous urticaria (CSU) is characterized by recurrent wheals lasting over 6 weeks, with various internal and external triggers implicated. Autoimmune progesterone dermatitis, a rare condition associated with cyclical urticaria in response to elevated progesterone levels, may overlap with CSU, particularly in women with menstrual cycle-related exacerbations. Objective: To document and analyze the timing of urticaria episodes in relation to the menstrual cycle to better understand this phenomenon. Methodology: This cross-sectional study was conducted at Omdurman Maternity Hospital and Omdurman Friendship Hospital in Sudan from January to June 2022. We included 75 women (ages 18-45) with CSU suspected to be linked to their menstrual cycle. Participants completed a structured questionnaire detailing demographic information, menstrual history, urticaria episodes, and associated symptoms. Results: Among the 75 participants, 46.7% experienced urticaria exacerbation coinciding with menstruation, primarily within the first 3 days. Another 33.3% reported premenstrual urticaria, while 20% had postmenstrual symptoms. The majority exhibited classic urticarial wheals, with only 3.7% experiencing angioedema. Premenstrual urticaria was significantly associated with the 21 to 30 age group ( Conclusion: This study highlights a significant association between the menstrual cycle and urticaria, suggesting that hormonal fluctuations play a key role in symptom exacerbation. These findings provide a basis for future research into the underlying mechanisms of hormonally influenced urticaria and the development of targeted therapeutic strategies, such as hormonal modulation or individualized treatment plans for affected patients.
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