Evidence map›Paper›PMID 40933357›Full record

ArticleGlobal challenges (Hoboken, NJ)2025

Techno-Economic and Lifecycle Analysis of Green Colloidal Silver: Moving toward Scale-Up.

Federico Trotta, Danielle Winning, Dea Bozhani, Seyedeh Fatemeh Mirpoor, Stella Lignou, Sameer Khalil Ghawi, Dimitris Charalampopoulos

Abstract read
In one paragraph

Article in Global challenges (Hoboken, NJ), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federico TrottaMetalchemy Limited 71-75 Shelton Street London WC2H 9JQ UK.ORCID https://orcid.org/0000-0002-9170-2029
Danielle WinningMetalchemy Limited 71-75 Shelton Street London WC2H 9JQ UK.ORCID https://orcid.org/0000-0002-4753-4697
Dea BozhaniMetalchemy Limited 71-75 Shelton Street London WC2H 9JQ UK.
Seyedeh Fatemeh MirpoorDepartment of Food and Nutritional Sciences University of Reading P.O. Box 226, Whiteknights Reading RG6 6AP UK.
Stella LignouDepartment of Food and Nutritional Sciences University of Reading P.O. Box 226, Whiteknights Reading RG6 6AP UK.
Sameer Khalil GhawiDepartment of Food and Nutritional Sciences University of Reading P.O. Box 226, Whiteknights Reading RG6 6AP UK.ORCID https://orcid.org/0000-0001-9787-9506
Dimitris CharalampopoulosDepartment of Food and Nutritional Sciences University of Reading P.O. Box 226, Whiteknights Reading RG6 6AP UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver particles (AgPs) are increasingly used across a range of industries, including personal care, household, and food packaging, but conventional synthesis methods involve high production costs and negative environmental impacts. Green synthesis using plant extracts offers a sustainable alternative, though limited comparative data on economic and environmental performance exist. This study evaluates three green methods-BX3 (a patented extract), lemon juice (LJ), and green tea (GT)-against a conventional method using sodium borohydride (NaBH₄). Equal-volume reactions are analyzed via ICP-MS, UV-vis spectroscopy, and dynamic light scattering. Techno-economic analysis and life cycle assessment (LCA) assessed costs and environmental impact. BX3 emerged as the most cost-effective and environmentally friendly option, producing AgPs at $13,000/kg with a 75% yield and a global warming potential of 1,900 kg CO₂-Eq/kg. In contrast, NaBH₄ yielded 7.35% at $195,000/kg, 15x more expensive than the BX3 method, and a global warming potential of 74,000 kg CO₂-Eq/kg. GT, while a green method, has the highest cost $690,000/kg, the lowest yield (1.13%), and the worst environmental impact, including a human toxicity value of 92,000 kg 1,4-DCB-Eq/kg-even surpassing the toxic NaBH₄ process. These findings highlight BX3's promise for scalable, low-impact AgP production and broader industrial use.

Indexed as

advanced materialscolloidal silvergreen synthesislife‐cycle analysissustainable antimicrobialstechno‐economic analysis

Identifiers

PMID40933357
PMCPMC12418338

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.