Evidence map›Paper›PMID 40933211›Full record

ArticleRespirology case reports2025

The Paradox of Metachronous Lipoid Pneumonia.

Haruki Kobayashi

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Paradox of Metachronous Lipoid Pneumonia.Respirology case reports · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Haruki KobayashiDivision of Thoracic Oncology Shizuoka Cancer Center Shizuoka Japan.ORCID https://orcid.org/0000-0002-3386-8063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 70-year-old female patient diagnosed with stage IV EGFR-mutant non-small-cell lung cancer experienced three distinct instances of exogenous lipoid pneumonia while undergoing chemotherapy. Chest CT consistently revealed ground-glass opacities with a crazy-paving pattern, and bronchoscopy confirmed the presence of lipid-laden, CD163-positive foamy macrophages. It is noteworthy that each episode was associated with a distinct exogenous exposure: intranasal administration of petroleum jelly, prolonged utilisation of a kerosene heater, and subsequently, intranasal application of Junma Moisturising Oil. The localisation of all episodes to the right middle lobe was noted, and resolution was attained with the cessation of the offending agent. This is the first reported case of recurrent exogenous lipoid pneumonia in a single patient caused by multiple unrelated substances. This case underscores the diagnostic value of radiologic patterns, the significance of meticulous exposure history, and the necessity of contemplating alternative aetiologies in patients with new infiltrates during cancer therapy.

Indexed as

asynchronous inhalational exposuresdifferent oil‐based substancesexogenous lipoid pneumoniahaemoptysis

Identifiers

PMID40933211
PMCPMC12417102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.