Evidence map›Paper›PMID 40933210›Full record

ArticleRespirology case reports2025

Asymptomatic Neurosyphilis Presenting With Bilateral Pulmonary Nodules: A Case Report.

Hiroshi Takahashi, Tadashi Ishida

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hiroshi TakahashiDepartment of Respiratory Medicine Kurashiki Central Hospital Okayama Japan.ORCID https://orcid.org/0009-0004-8892-7624
Tadashi IshidaDepartment of Respiratory Medicine Kurashiki Central Hospital Okayama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, syphilis cases have been increasing and pulmonary lesions have been reported. However, asymptomatic neurosyphilis has not been documented. This condition is often unrecognised and presents with symptoms similar to those of other infectious and non-infectious lung diseases. In syphilitic pneumonia, defined as a secondary form of syphilis, intramuscular injection of benzylpenicillin (24 million units) remains the gold standard for treatment, with a favourable prognosis. This report presents for the first time a case of asymptomatic neurosyphilis with multiple pulmonary nodules and buttock lipodystrophy. If rapid plasma reagin (RPR) antibody titres are high and RPR testing is difficult during follow-up, cerebrospinal fluid (CSF) examination may be considered for further evaluation of asymptomatic neurosyphilis. This case showed a high expression of RPR (154 R.U.) and given the nature of the patient's work (long-distance transportation), short-term follow-up was difficult. Therefore, CSF was performed to enable early diagnosis and treatment.

Indexed as

asymptomatic neurosyphilismultiple pulmonary nodulesTreponema pallidum

Identifiers

PMID40933210
PMCPMC12417626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.