ArticlePsychedelic medicine (New Rochelle, N.Y.)2025
Ketamine-Assisted Group Therapy for Work-Related Stress in First Responders and Frontline Health Care Workers.
Article in Psychedelic medicine (New Rochelle, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ketamine-Assisted Psychotherapy for Posttraumatic Stress Disorder: A Systematic Review and Individual Participant Data Meta-Analysis of Predictors of Treatment Effects.Psychotherapy and psychosomatics · 2026Pooled it
- A scoping review: ketamine or esketamine when used to assist psychotherapy or in combination with psychotherapy for the management of depression in adults.Npj mental health research · 2026Article
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Authors and funding
4 authors.
Funding
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Abstract
Introduction: Ketamine is an evidenced-based treatment for depression, and it has shown promise in addressing many other mental health conditions related to work-related stress or burnout, such as anxiety and post-traumatic stress disorder. Ketamine-assisted psychotherapy (KAP) is part of an emerging model of psychedelic medicine that employs psychoactive agents to support the psychotherapeutic process. Frontline health care workers and first responders encountered excessive levels of job stress, especially during the COVID-19 pandemic. This article reports on a 6-week community-based group-KAP program to address symptoms of trauma, anxiety, and depression in a sample of first responders and frontline health care workers. Methods: Recruitment was self-directed based on a sense of work-related stress. All participants completed a 6-week ketamine-assisted psychotherapy group intervention with three to six participants per group. The group characteristics and repeated measures comparisons were analyzed via descriptive statistics, pre- and post-intervention measure comparisons and regression modeling. Results: Sixteen patients received KAP in small groups with "pre" and "post" treatment evaluation of anxiety (Generalized Anxiety Disorder-7), depression (Patient Health Questionnaire-9), and trauma (Posttraumatic Stress Disorder Checklist for the Conclusion: These results suggest that the community-based group-KAP program described here may be a useful treatment for work-related stress, though further formal evaluation is required. Future directions, limitations, and interpretations are discussed.
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