Evidence map›Paper›PMID 40933163›Full record

ArticleWorld journal of psychiatry2025

Effect of theta-transcranial alternating current stimulation on working memory performance among healthy adults: A systematic review and meta-analysis.

Tian-Ya Hou, Xiao-Fei Mao, Rui-Ke Zhang

Abstract read
In one paragraph

Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tian-Ya HouFaculty of Psychology, Naval Medical University, Shanghai 200433, China.
Xiao-Fei MaoFaculty of Psychology, Naval Medical University, Shanghai 200433, China.
Rui-Ke ZhangFaculty of Psychology, Naval Medical University, Shanghai 200433, China. zrk_2015@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorking memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks. Extensive neurophysiological research has established that theta oscillations (4-8 Hz) play an essential role in supporting working memory operations. Theta-band transcranial alternating current stimulation (tACS) offers a potential mechanism for working memory enhancement through direct modulation of these fundamental neural oscillations. Nevertheless, current empirical evidence shows substantial variability in the observed effects of theta-tACS across studies.

aimTo conduct a systematic review and meta-analysis evaluating the effects of theta-tACS on working memory performance in healthy adults.

methodsA systematic literature search was performed on PubMed, EMBASE, and Web of Science up to March 10, 2025. Effect sizes were computed using Hedges'

resultsThe systematic review included 21 studies (67 effect sizes). Initial meta-analysis showed theta-tACS moderately improved working memory (Hedges'

conclusionTheta-tACS enhances working memory in healthy adults, with effects modulated by the task type and protocol parameters, offering dual implications for cognitive enhancement and clinical interventions.

Indexed as

Delayed match-to-sample taskHealthy adultsN-backThetaTranscranial alternating current stimulationWorking memory

Identifiers

PMID40933163
PMCPMC12417929

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.