Evidence map›Paper›PMID 40933109›Full record

ArticleJournal of the Society for Cardiovascular Angiography & Interventions2025

Trends in Mortality Among Adults With Acute Myocardial Infarction With Cardiogenic Shock in the United States, 1999-2023.

Abdullah Naveed Muhammad, Sivaram Neppala, Himaja Dutt Chigurupati, Bazil Azeem, Rabia Iqbal, Muhammad Omer Rehan, Priya Hotwani, Ahila Ali, Sowjanya Kapaganti, Mushood Ahmed and 4 more

Abstract read
In one paragraph

Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abdullah Naveed MuhammadDepartment of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Sivaram NeppalaDivision of Cardiology, The University of Texas Health Sciences Center, San Antonio, Texas.
Himaja Dutt ChigurupatiDepartment of Internal Medicine, New York Medical College at Saint Michael's Medical Center, Newark, New Jersey.
Bazil AzeemDepartment of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Rabia IqbalDepartment of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Muhammad Omer RehanDepartment of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Priya HotwaniDepartment of Internal Medicine, Parkview Health, Fort Wayne, Indiana.
Ahila AliDepartment of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Sowjanya KapagantiDivision of Cardiology, Creighton University, Omaha, Nebraska.
Mushood AhmedDepartment of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
Mobeen Zaka HaiderDepartment of Cardiology, West Virginia University, Morgantown, West Virginia.
Yasar SattarDepartment of Cardiology, West Virginia University, Morgantown, West Virginia.
Jamal S RanaDepartment of Cardiology, The Permanente Medical Group, Oakland, California.
Sourbha DaniDepartment of Cardiology, Lahey Hospital and Medical Center, Burlington, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiogenic shock (CS) elevates mortality rates among patients with acute myocardial infarction (AMI), yet there are insufficient data on trends in mortality. This study seeks to elucidate demographic patterns and mortality statistics. Methods: We analyzed data from the Centers for Disease Control and Prevention's Wide-ranging ONline Data for Epidemiologic Research (1999-2023) to evaluate mortality related to CS among AMI patients aged 25 years and above. Age-adjusted mortality rates (AAMR) per 100,000 patients and average annual percentage changes were calculated using JoinPoint regression analysis to explore mortality trends. Results: Cardiogenic shock contributed to 187,838 deaths among AMI patients aged 25 years and older. Between 1999 and 2023, the AAMR fell from 5.4 to 3.3 per 100,000, reflecting an average annual percentage change of -2.02. The most significant reduction occurred from 1999 to 2011, followed by a notable increase from 2011 to 2021 (annual percent change, 3.32). Disparities are apparent, as men have higher AAMR than women (4.5 vs 2.5), with Hispanic individuals at the most significant risk (AAMR, 3.5), followed by Whites (AAMR, 3.4). Regionally, West Virginia has the highest AAMR at 5.3, whereas Minnesota has the lowest at 2.3. Additionally, rural areas report higher AAMR than urban ones (4.0 vs 3.2). Conclusions: The recent increase in mortality rates between 2011 and 2021 due to CS in AMI and disparities among men, Hispanic individuals, and people living in rural areas-calls for urgent attention. By applying focused interventions and improving health care access, we can bridge these gaps and enhance patient outcomes.

Indexed as

acute myocardial infarctioncardiogenic shockmortalityracesex

Identifiers

PMID40933109
PMCPMC12418409

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.