ArticleRSC advances2025
Biocatalytic cascade combining an engineered pyranose 2-oxidase and transaminases for the synthesis of amino sugars.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
This work reports cascade reactions using a pyranose 2-oxidase and transaminases for synthesizing the rare amino sugars mannosamine, glucosamine, and galactosamine. Transaminases were engineered to accept unnatural 2-keto-sugars, providing up to 68% galactosamine yield. The mechanisms of C2-amination by these transaminases were also investigated. These transaminase variants have potential applications in high-value amino sugar synthesis.
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Registered trials
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