Evidence map›Paper›PMID 40932627›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025

Outcomes of acute versus delayed multi-ligament knee injury reconstruction: A retrospective analysis with mean 3.6-year follow-up.

Shankar S Thiru, Alexander Boos, Jonathan Lawson, Nicholas Aksu, John Garside, George Hatch, Evan Argintar

Abstract readComparative Study
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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shankar S ThiruGeorgetown University Medical Center, Washington, DC, USA. sst61@georgetown.edu.
Alexander BoosGeorgetown University Medical Center, Washington, DC, USA.
Jonathan LawsonUniversity of Washington Medical Center, Seattle, USA.
Nicholas AksuGeorgetown University Medical Center, Washington, DC, USA.
John GarsideGeorgetown University Medical Center, Washington, DC, USA.
George HatchUniversity of Southern California, Los Angeles, USA.
Evan ArgintarMedStar Washington Hospital Center, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveMulti-ligament knee injuries (MLKIs) are debilitating injuries, often managed with surgical reconstruction. Our purpose was to determine whether acute or delayed reconstruction led to better functional and patient-reported outcomes. MATERIALS AND

methodsAn institutional dataset was queried for patients who underwent MLKI reconstruction from 2012 to 2019 and completed postoperative functional and patient-reported outcome surveys with minimum 2-year follow-up. Exclusion criteria included single ligament reconstruction, revision surgery, and periarticular tumors. Patient-reported outcomes measurement system (PROMIS) and multi-ligament quality of life (ML-QoL) outcomes were compared between patients who underwent acute (< 2 weeks) and delayed (> 2 weeks) reconstruction.

resultsThirty-three patients were included for analysis (16 acute, 17 delayed): mean follow-up 3.6 years, mean BMI 29.8 ± 5.9, mean age 37.7 ± 13.5, sex: 19(58%) females, 14(42%) males. At final follow-up, there was no statistical difference between groups in most PROMIS scores, including Lysholm knee score (63 vs. 72, p = 0.13), pain (53 vs. 47, p = 0.11), or mobility (45 vs. 49, p = 0.18). Patients who underwent delayed reconstruction demonstrated significantly higher physical function scores (46 vs. 53, p = 0.05). There was no statistical difference in majority of ML-QoL scores, including physical impairments (42 vs. 29, p = 0.09), emotional impairments (45 vs. 30, p = 0.12), and societal involvement (38 vs. 24, p = 0.09). Patients who underwent acute reconstruction reported statistically greater activity limitations than delayed reconstruction (36 vs. 21, p = 0.02). There were no significant differences in complication rates between groups.

conclusionDelayed MLKI reconstruction had comparable results to acute reconstruction for PROMIS and ML-QoL outcomes, and had greater physical function and lower activity limitation postoperatively. These data demonstrate that delayed reconstruction may be an appropriate management option for MLKI reconstruction. LEVEL OF EVIDENCE: Level III, Retrospective Cohort study.

Indexed as

Knee InjuriesLigaments, ArticularPlastic Surgery ProceduresAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient Reported Outcome MeasuresQuality of LifeRecovery of FunctionRetrospective StudiesTime FactorsTime-to-TreatmentTreatment OutcomeMulti-ligament knee reconstructionOrthopedic trauma injuriesTime to surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.