Evidence map›Paper›PMID 40932513›Full record

ArticleParasitology research2025

Hidden diversity and host specificity of bat trypanosomes in East and Central Africa.

Sadic Waswa Babyesiza, Alena Fornůsková, Abdul Katakweba, Eric Kigai, Kristýna Hadová, Jean Luther Ngbangui Kaguendo, Labo Dieu-Béni Sosthène Bonaventure, Primael Tabiti, Thierry Aebischer, Joëlle Goüy de Bellocq and 2 more

Abstract read
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Article in Parasitology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Sadic Waswa Babyesiza *Institute of Vertebrate Biology of the Czech Academy of Sciences, Brno, Czech Republic. waswasadic@gmail.com.ORCID http://orcid.org/0000-0002-9586-6944
Alena Fornůsková *Institute of Vertebrate Biology of the Czech Academy of Sciences, Brno, Czech Republic. fornuskova@ivb.cz.ORCID http://orcid.org/0000-0003-3319-8394
Abdul KatakwebaAfrica Centre of Excellence for Innovative Rodent Pest Management and Biosensor Technology Development (ACE IRPM&BTD), Institute of Pest Management Centre, Sokoine University of Agriculture, Morogoro, Tanzania.
Eric KigaiDepartment of Zoology, Entomology and Fisheries Science, Makerere University, Kampala, Uganda.
Kristýna HadováInstitute of Vertebrate Biology of the Czech Academy of Sciences, Brno, Czech Republic.
Jean Luther Ngbangui KaguendoUniversity of Bangui, Bangui, Central African Republic.
Labo Dieu-Béni Sosthène BonaventureUniversity of Bangui, Bangui, Central African Republic.
Primael TabitiAfrican Parks, Johannesburg, South Africa.
Thierry AebischerAfrican Parks, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-0470-0878
Joëlle Goüy de BellocqInstitute of Vertebrate Biology of the Czech Academy of Sciences, Brno, Czech Republic.ORCID http://orcid.org/0000-0001-5831-6284
Josef BryjaInstitute of Vertebrate Biology of the Czech Academy of Sciences, Brno, Czech Republic.ORCID http://orcid.org/0000-0003-0516-7742
Jan VotýpkaDepartment of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic. jan.votypka@natur.cuni.cz.ORCID http://orcid.org/0000-0002-0552-9363

Funding

Czech Science Foundation 20-07091J AND 23-06116S
6 · The paper itself

Abstract

Bats are recognized as key reservoir hosts for a variety of trypanosomes, yet their full diversity and host associations remain underexplored in Africa. In this study, we investigated the diversity and phylogenetic relationships of trypanosomes infecting bats in Uganda and the Central African Republic (CAR) using molecular tools. A total of 22 distinct genotypes were identified, clustering into seven well-supported phylogroups, including known species such as Trypanosoma dionisii, T. livingstonei, T. vespertilionis, and T. erneyi, alongside several novel lineages. Notably, T. erneyi was restricted to Mops condylurus, reaffirming its narrow host specificity. Phylogenetic analyses revealed substantial intraspecific diversity in T. livingstonei and T. vespertilionis, suggesting potential cryptic species, while T. dionisii exhibited limited genetic divergence across a broad geographic range. Intriguingly, a unique and highly diverse phylogroup was detected exclusively in fruit bats (Pteropodidae) from Uganda, closely related to the Australian T. teixeirae, and likely represents a novel species. The absence of trypanosomes in fruit bats from CAR, despite similar sampling effort, hints at ecological or evolutionary factors shaping parasite distribution. Our findings expand the current knowledge of bat-trypanosome diversity and highlight the importance of African bat populations in understanding the evolutionary dynamics of trypanosomes.

Indexed as

ChiropteraGenetic VariationHost SpecificityTrypanosomaTrypanosomiasisAnimalsCentral African RepublicGenotypePhylogenyUgandaAfrican ChiropteraBat trypanosomesHost specificityPhylogenetic diversity

Identifiers

PMID40932513
PMCPMC12425843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.