Evidence map›Paper›PMID 40932482›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2026

TAVI plus PCI versus SAVR plus CABG: Long-term outcome of a multicentre-registry.

A Stundl, L Preuss, A Prinzing, J C Voran, H Seoudy, I Mesanovic, V Obermeier, G Lutter, M Potratz, G Buglio and 14 more

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

A Stundl *Department of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
L Preuss *Department of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany. laura.preuss@tum.de.ORCID http://orcid.org/0009-0005-7352-1987
A Prinzing *Department of Cardiovascular Surgery, German Heart Center Munich, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
J C Voran *Department of Internal Medicine III, Cardiology and Critical Care, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
H SeoudyDepartment of Internal Medicine III, Cardiology and Critical Care, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
I MesanovicDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
V ObermeierDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
G LutterGerman Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Kiel, Germany.
M PotratzDepartment of General and Interventional Cardiology and Angiology, Herz- Und Diabetes-Zentrum, Bad Oeynhausen, Germany.
G BuglioDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
A PohlmeyerDepartment of Internal Medicine III, Cardiology and Critical Care, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
R ThalmannDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
P HoppmannDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
C BradaricDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
H RugeDepartment of Cardiovascular Surgery, German Heart Center Munich, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
M ErlebachDepartment of Cardiovascular Surgery, German Heart Center Munich, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
R LangeDepartment of Cardiovascular Surgery, German Heart Center Munich, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
K L LaugwitzDepartment of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.
T PühlerDepartment of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
T RudolphDepartment of General and Interventional Cardiology and Angiology, Herz- Und Diabetes-Zentrum, Bad Oeynhausen, Germany.
S BleizifferDepartment of Cardiothoracic Surgery, Herz- Und Diabetes-Zentrum, Bad Oeynhausen, Germany.
M KraneGerman Centre for Cardiovascular Research (DZHK), Partner Site Munich, Munich, Germany.
D Frank *Department of Internal Medicine III, Cardiology and Critical Care, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
C Kupatt *Department of Internal Medicine I, Cardiology, Klinikum Rechts Der Isar, TUM School of Medicine & Health, Technische Universität München, Munich, Germany.

Funding

DZHK 81X1600607
6 · The paper itself

Abstract

backgroundIn elderly patients with severe aortic stenosis (AS), concomitant coronary artery disease (CAD) is common. Escpecially for intermediate-risk patients eligible for both interventional and surgical treatment, long-term benefit of either approach remains unclear.

objectivesTo compare long-term outcomes of TAVI + PCI versus SAVR + CABG in intermediate-risk AS-CAD patients (logistic EuroSCORE 10-20%, EuroSCORE II 4-9%).

methodsThis retrospective multicentre study included 366 patients treated between 2012 and 2020: 211 underwent TAVI + PCI and 155 received SAVR + CABG. The primary endpoint was all-cause mortality up to three years; secondary outcomes followed VARC-3 criteria.

resultsMortality rates were similar at 30 days (4.8% vs. 8.4%, p = 0.16), six months (12.4% each), one year (18.1% vs. 15.7%) and two years (24.9% vs. 20.1%). At three years, mortality was higher after TAVI + PCI (37.1% vs. 25.5%, p = 0.02), though CAD complexity was greater in the SAVR + CABG group (SYNTAX Score 22.2 vs. 15.9, p < 0.001). TAVI + PCI patients were older (81.1 vs. 78.5 years, p < 0.001), but surgical risk was comparable (EuroSCORE II 6.4% vs. 6.2%). Surgical patients experienced more complications, including delirium, stroke, acute kidney injury, major bleedings and transfusion needs. After propensity score matching (154 patients per group), 3-year mortality no longer differed significantly (33.8% vs. 25.9%, p = 0.14).

conclusionBoth TAVI + PCI and SAVR + CABG yield comparable long-term outcomes in intermediate-risk AS-CAD patients. Although early complications were more common with surgery, there was a trend towards improved long-term survival.

Indexed as

Aortic ValveAortic Valve StenosisCoronary Artery BypassCoronary Artery DiseaseHeart Valve Prosthesis ImplantationPercutaneous Coronary InterventionRegistriesAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleRetrospective StudiesRisk FactorsSurvival RateAortic stenosisCoronary artery diseaseIntermediate riskSurgical aortic valve replacementTranscatheter aortic valve implantation

Identifiers

PMID40932482
PMCPMC13249651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.