Evidence map›Paper›PMID 40932201›Full record

ReviewCurrent opinion in HIV and AIDS2025

Integrating socio-behavioral, ethics, community, and translational science considerations in HIV cure research.

Karine Dubé, Ali Ahmed, John A Sauceda

Abstract readReview
In one paragraph

Review in Current opinion in HIV and AIDS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Intersectionality-Informed HIV Cure-Related Research at the End of Life: A Call to Action.International journal of environmental research and public health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karine DubéDivision of Infectious Diseases and Global Public Health (IDGPH), Department of Medicine, University of California San Diego (UCSD), La Jolla.
Ali AhmedDivision of Infectious Diseases and Global Public Health (IDGPH), Department of Medicine, University of California San Diego (UCSD), La Jolla.
John A SaucedaDivision of Prevention Science, Center for AIDS Prevention Studies (CAPS), University of California San Francisco (UCSF), San Francisco, California, USA.

Funding

BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination ImmunotherapyUM1AI164570 · NIAID · WISTAR INSTITUTE · PI Luis J Montaner, James L. Riley · 2021 to 2026
$34.7M
Investigating Psychosocial Experiences of HIV Cure Trial Participants Undergoing Extended HIV Treatment Interruptions: Implications for Ethical ConductR01MH126768 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DUBE, KARINE, SAUCEDA, JOHN ANDREW · 2021 to 2025
$3.6M
Integrating Trauma-Informed Research in Assessment of Young Women Engaged in HIV Cure Research (Post-Intervention Control) Trial with Analytical Treatment Interruption in Durban, South AfricaR21MH132406 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DUBE, KARINE · 2023 to 2023
$422k
NIAID NIH HHS UM1 AI164570NIMH NIH HHS R01 MH126768NIMH NIH HHS R21 MH132406
6 · The paper itself

Abstract

purpose of reviewHIV cure research efforts are expanding globally, yet several critical areas in the socio-behavioral, ethics, community engagement, and translational aspects remain underexplored. This article critically reviews the relevant literature from the past 5 years (2021-2025), highlights key gaps, and offers recommendations for future research. RECENT

findingsThe multidisciplinary literature on HIV cure research is expanding, but urgent attention is required in several areas. These include the integration of socio-behavioral, ethics, and community engagement perspectives into HIV cure trials, with an increased emphasis on translation to resource-limited settings. The intersection of socio-behavioral sciences, ethics, and translational science requires more tailored research to ensure the deployment of socially impactful interventions. SUMMARY: Critical areas for further research include: increased scholarship in socio-behavioral sciences and ethics alongside scientific advancements in HIV cure research; expanding formative research in resource-limited settings and enhancing integration within analytical treatment interruption (ATI)-inclusive trials; continued implementation of the behavioral and social sciences research functional framework and evidence-based approaches into trial designs; strengthening psychosocial support and ethical frameworks for trial participants; and redressing power imbalances between scientific disciplines, ensuring socio-behavioral, ethics and community considerations are central, not secondary, to HIV cure research efforts worldwide.

Indexed as

HIV InfectionsTranslational Research, BiomedicalTranslational Science, BiomedicalHumanscommunity engagementethicsHIV cure researchsocio-behavioral sciencestranslational science

Identifiers

PMID40932201
PMCPMC12431633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.