Evidence map›Paper›PMID 40932112›Full record

ArticleChemistryOpen2025

Metabolism of Epoxidised Withanolides by a Generalist and a Specialist Insect Species.

Marie Pauline Sell, Christian Paetz, Felix Feistel, David G Heckel, Yannick Pauchet

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemistryOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marie Pauline SellInstitute of Cell and Systems Biology of Animals, Molecular Evolutionary Biology, University of Hamburg, 20148, Hamburg, Germany.ORCID 0009-0002-9218-0661
Christian PaetzNMR/Biosynthesis Group, Max Planck Institute for Chemical Ecology, 07745, Jena, Germany.ORCID 0000-0002-5776-7574
Felix FeistelDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, 07745, Jena, Germany.ORCID 0000-0002-7085-4891
David G HeckelEmeritus Group Entomology, Max Planck Institute for Chemical Ecology, 07745, Jena, Germany.ORCID 0000-0001-8991-2150
Yannick PauchetDepartment of Insect Symbiosis, Max Planck Institute for Chemical Ecology, 07745, Jena, Germany.ORCID 0000-0002-2918-8946

Funding

Deutsche Forschungsgemeinschaft HE6350/1-2Max Planck Society
6 · The paper itself

Abstract

Major secondary metabolites of Physalis plants, epoxidized withanolides, have a potent feeding deterrent and growth inhibitory effect on most herbivorous insects. Caterpillars of the specialist moth species Heliothis (Chloridea) subflexa consume only Physalis fruits, whereas the closely related generalist Heliothis (Chloridea) virescens feeds on 14 different plant families, but not Physalis. The two species have different physiological responses to dietary withanolides, so it is wondered whether they metabolize withanolides differently. The Physalis peruviana plants are grown in a [

Indexed as

MothsPhysalisWithanolidesAnimalsChromatography, High Pressure LiquidMagnetic Resonance SpectroscopyPlant LeavesSpectrometry, Mass, Electrospray IonizationWithanolidesChlorideaHeliothisPhysalissubflexavirescenswithanolides

Identifiers

PMID40932112
PMCPMC12680557

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.