ArticleJournal of the American Heart Association2025
Demographics and Trends of Sudden Cardiac Death-Related Mortality in the United States, 1999 to 2022.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Trends and Demographic Disparities Among Adults With Sudden Cardiac Death and Diabetes Mellitus in the United States: A Nationwide Analysis.Journal of arrhythmia · 2026Article
- Genetic and epigenetic landscape of non-familial sudden cardiac death.Molecular biology reports · 2026Review
- Trends in sudden death-attributed mortality across Europe, 2010-2020: a retrospective population-based analysis.The Lancet regional health. Europe · 2026Article
- First Presentation of Atherosclerotic Cardiovascular Disease in Previously Healthy Individuals.Current cardiology reports · 2026Review
- [Subcutaneous defibrillator (S-ICD)].Herz · 2025Article
- Establishing a National Cardiopulmonary Resuscitation Program in Indian High schools and colleges: An expert collaborative call to action and implementation model.Indian pacing and electrophysiology journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a paucity of data regarding mortality trends among individuals experiencing sudden cardiac death (SCD). Therefore, we aimed to investigate the trends in SCD-related mortality across all age groups in the United States.
methodsThis retrospective cohort analysis used the US Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research data from 1999 to 2022. The study focused on patients of all age groups with SCD listed as either a contributing or underlying cause of death. Age-adjusted mortality rates per 100 000 were calculated and stratified by sex, race, ethnicity, region, state, and place of death.
resultsA total of 311 218 SCD-related deaths were reported. Overall, age-adjusted mortality rates declined from 4.52 (95% CI, 4.44-4.60) in 1999 to 3.51 (95% CI, 3.43-3.56) in 2022. A downward trend was observed from 1999 to 2018 (APC, -1.94 [95% CI, -2.23 to -1.69]), followed by a sharp rise from 2018 to 2022 (APC, 7.07 [95% CI, 3.38-9.46]). Men consistently had higher age-adjusted mortality rates than women (5.23 versus 2.71). Non-Hispanic Black individuals had the highest age-adjusted mortality rates (5.66), and Non-Hispanic Asians had the lowest (1.23). Mortality rates were greater in nonmetropolitan and southern US regions. States in the upper 90th percentile (eg, Mississippi, North Carolina) had markedly higher mortality burdens than those in the lower 10th percentile (eg, Arizona, Maryland). Individuals aged ≥85 years had the highest crude mortality rate (51.3).
conclusionsAlthough SCD-related mortality declined over 2 decades, rates have risen significantly since 2018. Persistent disparities by sex, race, geography, and age call for urgent, targeted public health interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.