Evidence map›Paper›PMID 40931978›Full record

ArticlePediatric pulmonology2025

The Impact of Race and Ethnicity on Congenital Diaphragmatic Hernia 1-Year Mortality.

Stephanie M Tsoi, Kayla L Karvonen, Martina A Steurer, Roberta L Keller

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Stephanie M TsoiDivision of Critical Care Medicine, Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-0115-5843
Kayla L KarvonenDivision of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
Martina A SteurerDivision of Critical Care Medicine, Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.
Roberta L KellerDivision of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.

Funding

Multidisciplinary Research Training in Pediatric Pulmonary Vascular DiseaseT32HL160508 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Steven Herbert Abman, Eric Douglas Austin · 2022 to 2026
$1.7M
Identifying and addressing family-prioritized social drivers of health to improve the long-term health of Black preterm infantsK23MD019349 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kayla Karvonen · 2024 to 2026
$512k
NHLBI NIH HHS T32 HL160508NIMHD NIH HHS K23 MD019349This study was supported by the National Institutes of Health (T32HL160508-01A1 [SMT], 1K23MD019349-01 [KLK]).
6 · The paper itself

Abstract

objectivesTo evaluate disparities in 1-year mortality in infants with congenital diaphragmatic hernia (CDH) by maternal race/ethnicity in a US population-based dataset, and to quantify mediation effects of socioeconomic status (SES) and maternal and neonatal medical factors. STUDY

designWe identified infants with CDH from the US Natality Database (2014-2019) that links birth and death certificates to 1-year of age. Primary outcome was 1-year mortality. Primary predictor was maternal race/ethnicity. Candidate mediators (SES [defined by maternal education level and public insurance status] and neonatal and maternal factors) were assessed using structural equation modeling.

resultsAmong 2589 infants with CDH, 1-year mortality was 28.4% (n = 734). Infant mortality differed by maternal race/ethnicity: Non-Hispanic White 25.5%, Black 39.1%, Hispanic 31.2%. Mortality differences persisted in multivariate analysis. Mediation analyses showed that SES accounted for 54.1% (20.4-68.6%) of the disparity between infants of Non-Hispanic White and Hispanic mothers. In contrast, SES accounted for only 17.1% (3.6-37.4%) of the disparity between infants of Non-Hispanic White and Black mothers, while the unmeasured remaining effect of race/ethnicity contributed 75.9% (49.5-91.1%).

conclusionsIn CDH, SES accounts for a large proportion of the mortality disparity for infants of Hispanic mothers while the remaining effect of race, aside from SES and neonatal factors, accounts for a large proportion of the mortality disparity for infants of Black mothers. The remaining effect of maternal race may be due to unmeasured aspects of SES, such as social determinants of health, and structural and systemic racism and bias.

Indexed as

EthnicityHernias, Diaphragmatic, CongenitalInfant MortalityRacial GroupsAdultBlack or African AmericanFemaleHispanic or LatinoHumansInfantInfant, NewbornMaleMothersSocial ClassUnited StatesWhiteCDHhealth disparitiesinfant mortalityneonatal intensive careraceracism

Identifiers

PMID40931978
PMCPMC12424093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.